Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | AHCY | P23526 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14472890 | 1.00 | PI4KA (0.43) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL14473043 | 0.87 | PI4KA (0.45) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL10284145 | 0.75 | AHCY (0.60) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL14472999 | 0.75 | AHCY (0.60) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL13248702 | 0.74 | ATM (0.43) | AHCYADORA2A | |
| SCHEMBL14139510 | 0.72 | AHCY (0.56) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL14379019 | 0.72 | ADORA2A (0.60) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL11347140 | 0.69 | POLB (0.54) | CHKANSD3 | |
| SCHEMBL18984365 | 0.69 | PIK3CD (0.46) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL14030163 | 0.68 | AHCY (0.40) | PI4KAPI4K2BPI4K2API4KBEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767657-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2010-08-03 | — | — | US | disclosed |