Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.50 |
| ▸ | CCR3 | P51677 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CHKA | P35790 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11352914 | 0.90 | NSD3 (0.52) | POLBCCR3LMNACHKADRD4 | |
| SCHEMBL11349449 | 0.89 | PIK3CD (0.46) | POLBLMNAALDH1A1DRD4MEN1 | |
| SCHEMBL11352141 | 0.88 | HTR1A (0.50) | MCHR1DRD4ADCY5 | |
| SCHEMBL11345878 | 0.87 | ADRA1D (0.54) | POLBADCY5 | |
| SCHEMBL11342542 | 0.84 | ADCY5 (0.50) | ALDH1A1ADCY5 | |
| SCHEMBL11476823 | 0.84 | ADCY5 (0.48) | LMNAALDH1A1TSHRADCY5 | |
| SCHEMBL11339731 | 0.83 | ADCY5 (0.48) | ADCY5 | |
| SCHEMBL11340014 | 0.82 | MEN1 (0.48) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL11475372 | 0.82 | ADCY5 (0.48) | MCHR1DRD4NSD3ADCY5 | |
| SCHEMBL11485738 | 0.82 | ADCY5 (0.48) | MCHR1CCR3NSD3ADCY5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003558-B1 | 9-(3-PIPERIDINOPROPYL)-PURINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1981-10-21 | — | — | EP | disclosed |
| US-4212866-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANTIEDEMIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1980-07-15 | — | — | US | disclosed |
| EP-0003558-A1 | 9-(3-Piperidinopropyl)-purine derivatives, processes for their preparation, their use and pharmaceutical compositions containing them | Roche Diagnostics GmbH (DE) | 1979-08-22 | — | — | EP | disclosed |