Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | AHCY | P23526 | 4/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14472890 | 0.84 | PI4KA (0.43) | EGFRSRCKDRAHCYADORA2A | |
| SCHEMBL13248700 | 0.84 | PI4KA (0.43) | EGFRSRCKDRAHCYADORA2A | |
| SCHEMBL10284145 | 0.77 | AHCY (0.60) | AHCYADORA2AALDH1A1PI4KAPI4K2B | |
| SCHEMBL14472999 | 0.77 | AHCY (0.60) | AHCYADORA2AALDH1A1PI4KAPI4K2B | |
| SCHEMBL13248702 | 0.76 | ATM (0.43) | AHCYADORA2AALDH1A1 | |
| SCHEMBL14472889 | 0.76 | ATM (0.43) | AHCYADORA2AALDH1A1 | |
| SCHEMBL14139510 | 0.74 | AHCY (0.56) | AHCYADORA2AALDH1A1PI4KAPI4K2B | |
| SCHEMBL15606513 | 0.72 | ADORA2A (0.57) | AHCYADORA2AALDH1A1PI4KAPI4K2B | |
| SCHEMBL3802976 | 0.72 | EGFR (0.61) | EGFRSRCKDRPI4KAPI4K2B | |
| SCHEMBL14379019 | 0.72 | ADORA2A (0.60) | AHCYADORA2AALDH1A1PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767657-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2010-08-03 | — | — | US | disclosed |