Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 3/20 | 0.37 |
| ▸ | GSK3B | P49841 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | BCAT1 | P54687 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2782445 | 0.78 | KDM4E (0.38) | GSK3AGSK3BGAAMAPTCYP3A4 | |
| SCHEMBL11206288 | 0.70 | MAPK1 (0.50) | GSK3AGSK3BGAAMAPTCYP3A4 | |
| SCHEMBL5759510 | 0.69 | KDM4E (0.45) | GSK3AGSK3BGAAALDH1A1HPGD | |
| SCHEMBL1258272 | 0.66 | KDM4E (0.49) | GSK3AGSK3BGAACYP3A4ALDH1A1 | |
| SCHEMBL7084390 | 0.64 | GAA (0.44) | GSK3AGSK3BGAAALDH1A1HPGD | |
| SCHEMBL19377934 | 0.63 | GRIA1 (0.50) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL2783188 | 0.62 | KDM4E (0.41) | GSK3AGSK3BALDH1A1HPGDKDM4E | |
| SCHEMBL2781441 | 0.62 | LMNA (0.43) | GSK3AGSK3BGAAMAPTALDH1A1 | |
| SCHEMBL11306236 | 0.62 | MAPT (0.52) | GSK3AGSK3BGAAMAPTCYP3A4 | |
| SCHEMBL10059379 | 0.61 | ATM (0.43) | GAAMAPTALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100179185-A1 | Novel Aminothienopyridinone Derivatives Processes for Preparing Them and Pharmaceutical Compositions Thereof | UCB PHARMA, S.A. (BE) | 2010-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179185-A1 | Novel Aminothienopyridinone Derivatives Processes for Preparing Them and Pharmaceutical Compositions Thereof | AASDHPPT, PTMS, TPMT | GSK3A 3140/4885GSK3B 2806/4885GAA 2546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.