Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PLAU | P00749 | 2/20 | 0.36 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2516696 | 1.00 | HPGD (0.46) | HPGDHTTKDM4EMAPTGAA | |
| SCHEMBL2516694 | 1.00 | HPGD (0.46) | HPGDHTTKDM4EMAPTGAA | |
| SCHEMBL4272121 | 0.87 | HPGD (0.55) | HPGDHTTKDM4EMAPTALDH1A1 | |
| SCHEMBL4272126 | 0.87 | HPGD (0.55) | HPGDHTTKDM4EMAPTALDH1A1 | |
| SCHEMBL17548944 | 0.78 | IDO1 (0.54) | HPGDHTTKDM4EMAPTGCGR | |
| SCHEMBL17988288 | 0.78 | IDO1 (0.54) | HPGDHTTKDM4EMAPTGCGR | |
| SCHEMBL1036073 | 0.77 | AXL (0.46) | HPGDHTTKDM4EPLAUNPC1 | |
| SCHEMBL1036074 | 0.77 | AXL (0.46) | HPGDHTTKDM4EPLAUNPC1 | |
| SCHEMBL9972003 | 0.76 | RXFP1 (0.38) | HPGDHTTKDM4EMAPTALDH1A1 | |
| SCHEMBL2510894 | 0.76 | HPGD (0.46) | HPGDHTTKDM4EMAPTGCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9095138-B2 | Isoxazoline insecticides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-08-04 | — | — | US | disclosed |
| US-20150098928-A9 | ISOXAZOLINE INSECTICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-04-09 | — | — | US | disclosed |
| US-20140127165-A1 | ISOXAZOLINE INSECTICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-05-08 | — | — | US | disclosed |
| US-8623875-B2 | Isoxazoline insecticides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-01-07 | — | — | US | disclosed |
| US-20100179195-A1 | ISOXAZOLINE INSECTICIDES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2010-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150098928-A9 | ISOXAZOLINE INSECTICIDES | CBR3, CYP4X1, PRDX1 | HPGD 3748/4885HTT 3257/4885KDM4E 3027/4885 |
| US-20140127165-A1 | ISOXAZOLINE INSECTICIDES | CBR3, CYP4X1, PRDX1 | HPGD 3748/4885HTT 3257/4885KDM4E 3027/4885 |
| US-20100179195-A1 | ISOXAZOLINE INSECTICIDES | CBR3, CYP4X1, PRDX1 | HPGD 3748/4885HTT 3257/4885KDM4E 3027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.