SCHEMBL13249706

SCHEMBL13249706

Cc1ccc(-n2c3ccc(N(c4ccc(N(c5ccccc5)c5ccccc5)cc4)c4ccc5c(c4)c4cc([Si](c6ccccc6)(c6ccccc6)c6ccccc6)ccc4n5-c4ccc(C)cc4)cc3c3cc([Si](c4ccccc4)(c4ccccc4)c4ccccc4)ccc32)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.37
POLB P06746 1/20 0.33
MAPT P10636 4/20 0.32
KDM4E B2RXH2 7/20 0.32
GAA P10253 2/20 0.32
HTT P42858 2/20 0.32
CYP2C9 P11712 2/20 0.32
GFER P55789 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.31
ATM Q13315 1/20 0.31
SMN1; SMN2 Q16637 4/20 0.31
HPGD P15428 4/20 0.31
ALDH1A1 P00352 4/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
HSD17B10 Q99714 2/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
CASP1 P29466 1/20 0.31
CASP7 P55210 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13249699 1.00 APP (0.37) APPPOLBMAPTKDM4EGAA
SCHEMBL13249698 0.99 APP (0.35) APPPOLBMAPTKDM4EGAA
SCHEMBL12721694 0.98 APP (0.34) APPPOLBMAPTKDM4EGAA
SCHEMBL12721739 0.98 APP (0.34) APPPOLBMAPTKDM4EGAA
SCHEMBL12721708 0.96 KDM4E (0.35) APPPOLBMAPTKDM4EGAA
SCHEMBL13249693 0.96 KDM4E (0.35) APPPOLBMAPTKDM4EGAA
SCHEMBL12879544 0.96 APP (0.36) APPPOLBMAPTKDM4EGAA
SCHEMBL12721846 0.94 POLB (0.35) APPPOLBMAPTHTTSMN1; SMN2
SCHEMBL13249737 0.94 CYP2C9 (0.35) APPPOLBMAPTKDM4EGAA
SCHEMBL13249713 0.94 CYP2C9 (0.35) APPPOLBMAPTKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7754349-B2 Silanylamine-based compound and organic light-emitting device including organic layer including the silanylamine-based compound SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-07-13 US disclosed
US-20080171227-A1 SILANYLAMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANIC LAYER INCLUDING THE SILANYLAMINE-BASED COMPOUND SAMSUNG SDI CO., LTD. (KR) 2008-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080171227-A1 SILANYLAMINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANIC LAYER INCLUDING THE SILANYLAMINE-BASED COMPOUND ADRB2, ADRB1, ADRB3 APP 1853/4885POLB 3497/4885MAPT 2255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.