Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | F12 | P00748 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13250582 | 0.88 | PLAU (0.42) | PLAUCYP2A6F12NCF1NOS3 | |
| SCHEMBL31098956 | 0.84 | PLAU (0.47) | PLAUCYP2A6F12NCF1NOS3 | |
| SCHEMBL16484700 | 0.84 | PLAU (0.47) | PLAUCYP2A6F12NCF1NOS3 | |
| SCHEMBL13250568 | 0.81 | KEAP1 (0.36) | NPC1RAB9AMAPTKDM4EL3MBTL1 | |
| SCHEMBL13250580 | 0.80 | PLAU (0.43) | PLAUCYP2A6F12NCF1NOS3 | |
| SCHEMBL13321038 | 0.79 | PLAU (0.38) | PLAUCYP2A6F12NCF1NOS3 | |
| SCHEMBL13320976 | 0.78 | PLAU (0.37) | PLAUCYP2A6F12NCF1NOS3 | |
| SCHEMBL13320994 | 0.78 | PLAU (0.37) | PLAUCYP2A6F12NCF1NOS3 | |
| SCHEMBL13320991 | 0.78 | PLAU (0.37) | PLAUCYP2A6F12NCF1NOS3 | |
| SCHEMBL16144422 | 0.77 | PLAU (0.36) | PLAUCYP2A6F12NCF1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100176377-A1 | Polymeric compound and polymeric electroluminescence element using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-07-15 | — | — | US | disclosed |
| US-20100176377-A1 | Polymeric compound and polymeric electroluminescence element using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-07-15 | — | — | US | disclosed |