Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 9/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 9/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | CSF1R | P07333 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13250573 | 0.86 | KDM4E (0.34) | KEAP1NFE2L2ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL13250594 | 0.82 | L3MBTL1 (0.35) | KEAP1NFE2L2ALDH1A1KDM4ECYP2D6 | |
| SCHEMBL13250595 | 0.81 | PLAU (0.38) | KEAP1NFE2L2ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL10110902 | 0.74 | ALDH1A1 (0.44) | KEAP1NFE2L2ALDH1A1TDP1KDM4E | |
| SCHEMBL12888139 | 0.72 | ALDH1A1 (0.42) | KEAP1NFE2L2ALDH1A1TDP1KDM4E | |
| SCHEMBL707336 | 0.72 | ALDH1A1 (0.42) | ALDH1A1TDP1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL4887896 | 0.70 | ALDH1A1 (0.52) | KEAP1NFE2L2ALDH1A1TDP1KDM4E | |
| SCHEMBL8900055 | 0.69 | EGFR (0.69) | EGFRCSF1RL3MBTL1NPC1RAB9A | |
| SCHEMBL16484702 | 0.69 | PRKCZ (0.40) | ALDH1A1TDP1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL31098956 | 0.69 | PLAU (0.47) | ALDH1A1TDP1KDM4ECYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100176377-A1 | Polymeric compound and polymeric electroluminescence element using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-07-15 | — | — | US | disclosed |
| US-20100176377-A1 | Polymeric compound and polymeric electroluminescence element using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-07-15 | — | — | US | disclosed |