⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL41781 | 0.64 | — | — | |
| SCHEMBL19382324 | 0.61 | ALDH1A1 (0.31) | — | |
| SCHEMBL5014669 | 0.60 | — | — | |
| SCHEMBL231463 | 0.60 | — | — | |
| Hydrochloric Acid SCHEMBL7192891 | 0.60 | — | — | |
| SCHEMBL5581970 | 0.57 | — | — | |
| SCHEMBL9397424 | 0.57 | — | — | |
| SCHEMBL10346404 | 0.57 | ALDH1A1 (0.50) | — | |
| SCHEMBL28659823 | 0.57 | — | — | |
| SCHEMBL23671 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280962-B1 | PROCESS FOR PREPARING 4-ACETOXY-3-HYDROXYETHYLAZETIDIN-2-ONE DERIVATIVES | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-05-13 | — | — | EP | claimed |
| US-4914199-A | REACTING PROTECTED BETA-LACTAM WITH ACETIC ANHYDRIDE IN PRESENCE OF BASE AND ACID CATALYST | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-04-03 | — | — | US | claimed |
| EP-0280962-A1 | Process for preparing 4-acetoxy-3-hydroxyethylazetidin-2-one derivatives | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-09-07 | — | — | EP | claimed |
| US-8182695-B2 | Bridged macrocyclic module compositions | WHITEFORD JEFFERY A (US) | 2012-05-22 | — | — | US | disclosed |
| US-8058261-B2 | 3′-ethynylcytidine derivative | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2011-11-15 | — | — | US | disclosed |
| EP-2045258-B1 | 3'-ETHYNYLCYTIDINE DERIVATIVE | TAIHO PHARMACEUTICAL CO LTD (JP) | 2011-09-21 | — | — | EP | disclosed |
| US-20090306008-A1 | 3'-ETHYNYLCYTIDINE DERIVATIVE | Sasaki, Takuma (JP) | 2009-12-10 | — | — | US | disclosed |
| EP-2045258-A1 | 3'-ETHYNYLCYTIDINE DERIVATIVE | Taiho Pharmaceutical Co., Ltd. (JP) | 2009-04-08 | — | — | EP | disclosed |
| US-20080290034-A1 | Bridged macrocyclic module compositions | COVALENT PARTNERS LLC | 2008-11-27 | — | — | US | disclosed |
| US-7368564-B2 | Bridged macrocyclic module compositions | COVALENT PARTNERS, LLC (US) | 2008-05-06 | — | — | US | disclosed |
| EP-1114815-B1 | Process to prepare taxol | UPJOHN CO (US) | 2004-09-29 | — | — | EP | disclosed |
| US-4914199-A | REACTING PROTECTED BETA-LACTAM WITH ACETIC ANHYDRIDE IN PRESENCE OF BASE AND ACID CATALYST | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-04-03 | — | — | US | disclosed |
| US-4892962-A | FROM ALLYL DIFLUOROACETATES AND A MONOCHLORO=SILANE, ADDITION POLYMERS | CIBA-GEIGY CORPORATION (US) | 1990-01-09 | — | — | US | disclosed |
| US-4806667-A | Promoting production of useful livestock with silylated aminophenylethylamine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-21 | — | — | US | disclosed |
| EP-0280962-A1 | Process for preparing 4-acetoxy-3-hydroxyethylazetidin-2-one derivatives | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-09-07 | — | — | EP | disclosed |
| EP-0247378-A1 | Process for preparing 4-acetoxy-3-hydroxyethylazetidin-2-one derivatives | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1987-12-02 | — | — | EP | disclosed |
| US-4692536-A | Process for the preparation of hemiaminals, and the use thereof | CIBA-GEIGY CORPORATION (US) | 1987-09-08 | — | — | US | disclosed |
| EP-0009201-B1 | SELECTIVELY PROTECTED 4,6-DI-O-(AMINOGLYCOSYL)-1,3-DIAMINOCYCLITOLS, METHOD FOR THEIR PREPARATION AND THEIR USE AS INTERMEDIATES | BAYER AG (DE) | 1981-12-02 | — | — | EP | disclosed |
| US-4294959-A | Selectively protected 4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols and their production | BAYER AKTIENGESELLSCHAFT (DE) | 1981-10-13 | — | — | US | disclosed |
| EP-0009201-A1 | Selectively protected 4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols, method for their preparation and their use as intermediates | BAYER AG (DE) | 1980-04-02 | — | — | EP | disclosed |