SCHEMBL13252860

SCHEMBL13252860

Cc1ccc2oc(C=Cc3ccc(-c4nc5cc(C)ccc5o4)s3)nc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SNCA P37840 1/20 0.49
▸ KDM4E B2RXH2 10/20 0.49
▸ ALDH1A1 P00352 10/20 0.49
▸ HPGD P15428 9/20 0.49
▸ RAB9A P51151 9/20 0.49
▸ SMN1; SMN2 Q16637 9/20 0.49
▸ NPC1 O15118 7/20 0.49
▸ HSD17B10 Q99714 7/20 0.49
▸ TP53 P04637 5/20 0.49
▸ CASP3 P42574 4/20 0.47
▸ SENP7 Q9BQF6 4/20 0.47
▸ SENP6 Q9GZR1 4/20 0.47
▸ SENP8 Q96LD8 3/20 0.47
▸ POLB P06746 1/20 0.47
▸ F2RL3 Q96RI0 3/20 0.46
▸ NFKB1 P19838 5/20 0.43
▸ NFKB2 Q00653 5/20 0.43
▸ RELA Q04206 5/20 0.43
▸ L3MBTL1 Q9Y468 3/20 0.43
▸ MAPT P10636 5/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31239357 0.82 KDM4E (0.65) KDM4EALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL318302 0.82 KDM4E (0.65) KDM4EALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL553697 0.81 SNCA (0.68) SNCAKDM4EALDH1A1HPGDRAB9A
SCHEMBL29924040 0.81 SNCA (0.68) SNCAKDM4EALDH1A1HPGDRAB9A
SCHEMBL30487871 0.81 SNCA (0.68) SNCAKDM4EALDH1A1HPGDRAB9A
SCHEMBL23827506 0.81 SNCA (0.68) SNCAKDM4EALDH1A1HPGDRAB9A
SCHEMBL553696 0.81 SNCA (0.68) SNCAKDM4EALDH1A1HPGDRAB9A
SCHEMBL14579739 0.81 SNCA (0.68) SNCAKDM4EALDH1A1HPGDRAB9A
SCHEMBL13928214 0.77 NPC1 (0.58) KDM4EALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL515859 0.75 KDM4E (0.68) SNCAKDM4EALDH1A1HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7763883-B2 Image display device FUJIFILM CORPORATION (JP) 2010-07-27 — — US disclosed
US-7763883-B2 Image display device FUJIFILM CORPORATION (JP) 2010-07-27 — — US disclosed
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