Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13253149 | 0.71 | CRBN (0.33) | — | |
| SCHEMBL489054 | 0.70 | FFAR3 (0.36) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL8529431 | 0.70 | TSHR (0.41) | PKMMCL1TSHRUSP2MMP1 | |
| SCHEMBL16357112 | 0.70 | USP2 (0.37) | PKMMCL1TSHRUSP2MMP1 | |
| SCHEMBL4031782 | 0.69 | — | — | |
| SCHEMBL13904083 | 0.68 | TSHR (0.37) | PKMTSHRUSP2MMP1MMP2 | |
| SCHEMBL3103479 | 0.68 | PKM (0.37) | PKMTSHRUSP2MMP1MMP2 | |
| SCHEMBL13412852 | 0.68 | TSHR (0.37) | PKMTSHRUSP2MMP1MMP2 | |
| SCHEMBL6367590 | 0.68 | PKM (0.37) | PKMMCL1TSHRUSP2MMP1 | |
| SCHEMBL12497824 | 0.67 | FFAR3 (0.33) | TSHRCHRM1AKR1A1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754684-B2 | Macromolecular platinum chelates | ACCESS PHARMACEUTICALS, INC. (US) | 2010-07-13 | — | — | US | disclosed |