SCHEMBL13253149

SCHEMBL13253149

CC(=O)NC(=O)C(C=O)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.33
NFKB1 P19838 2/20 0.32
FFAR3 O14843 1/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
TAS2R38 P59533 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MAPT P10636 1/20 0.30
THRB P10828 1/20 0.30
ALOX15 P16050 1/20 0.30
PTGS2 P35354 1/20 0.30
THPO P40225 1/20 0.30
RECQL P46063 1/20 0.30
BLM P54132 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18557228 0.76 FFAR2 (0.31)
SCHEMBL1162335 0.72
SCHEMBL13253147 0.71 PKM (0.35)
SCHEMBL4031782 0.71
SCHEMBL28775457 0.70 FFAR3 (0.39) FFAR3LCKFYN
Diacetamide SCHEMBL28386543 0.68 FFAR3 (0.58) CRBNNFKB1FFAR3LCKFYN
Diacetamide SCHEMBL29069322 0.68 FFAR3 (0.58) CRBNNFKB1FFAR3LCKFYN
SCHEMBL27523293 0.67 SMN1; SMN2 (0.44) SMN1; SMN2
SCHEMBL25458289 0.65
Diacetamide SCHEMBL635653 0.65 FFAR3 (0.54) CRBNNFKB1FFAR3LCKFYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7754684-B2 Macromolecular platinum chelates ACCESS PHARMACEUTICALS, INC. (US) 2010-07-13 US disclosed