Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 2/20 | 0.58 |
| ▸ | MGLL | Q99685 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 6/20 | 0.51 |
| ▸ | MGAM | O43451 | 5/20 | 0.51 |
| ▸ | AMY1A | P0DUB6 | 5/20 | 0.51 |
| ▸ | SI | P14410 | 5/20 | 0.51 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | F2 | P00734 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.45 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.45 |
| ▸ | F12 | P00748 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8221643 | 0.94 | ASAH1 (0.64) | ASAH1MGLLGAAMGAMAMY1A | |
| SCHEMBL8221504 | 0.82 | ASAH1 (0.60) | ASAH1MGLLGAAMGAMAMY1A | |
| SCHEMBL8218832 | 0.80 | ASAH1 (0.57) | ASAH1MGLLGAAMGAMAMY1A | |
| SCHEMBL427517 | 0.79 | ASAH1 (0.70) | ASAH1MGLLGAAMGAMAMY1A | |
| SCHEMBL20150832 | 0.79 | ASAH1 (0.71) | ASAH1MGLLGAAMGAMAMY1A | |
| SCHEMBL12593813 | 0.77 | ASAH1 (0.83) | ASAH1MGLLGAAMGAMAMY1A | |
| SCHEMBL8218121 | 0.75 | ASAH1 (0.50) | ASAH1MGLLGAAMGAMAMY1A | |
| Malonic Acid SCHEMBL8211367 | 0.75 | GAA (0.61) | ASAH1MGLLGAAMGAMAMY1A | |
| SCHEMBL12593872 | 0.75 | ASAH1 (0.93) | ASAH1MGLLGAAMGAMAMY1A | |
| SCHEMBL426720 | 0.74 | GAA (0.59) | ASAH1MGLLGAAMGAMAMY1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754684-B2 | Macromolecular platinum chelates | ACCESS PHARMACEUTICALS, INC. (US) | 2010-07-13 | — | — | US | disclosed |