Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13256272 | 1.00 | TAAR1 (0.40) | TAAR1APPTRPV1CYP3A4IDO1 | |
| SCHEMBL12171 | 0.79 | TAAR1 (0.62) | TAAR1APPCYP3A4IDO1 | |
| SCHEMBL13663204 | 0.78 | APP (0.38) | APPTRPV1 | |
| SCHEMBL3703681 | 0.74 | TAAR1 (0.40) | TAAR1APP | |
| SCHEMBL3703684 | 0.74 | TAAR1 (0.40) | TAAR1APP | |
| SCHEMBL663449 | 0.74 | APP (0.39) | APPTRPV1CYP3A4PDE2A | |
| Hydrochloric Acid SCHEMBL7678986 | 0.74 | KIF11 (0.52) | TAAR1CYP3A4IDO1 | |
| SCHEMBL7194949 | 0.72 | CA2 (0.40) | APPTRPV1 | |
| SCHEMBL2436188 | 0.72 | APP (0.52) | APPTRPV1 | |
| SCHEMBL28781680 | 0.72 | APP (0.52) | APPTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010087982-A1 | GLUR2 RECEPTOR MODULATORS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2010-08-05 | — | — | WO | disclosed |
| US-20090270508-A1 | GluR2 receptor modulators | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-10-29 | — | — | US | disclosed |
| US-20090270508-A1 | GluR2 receptor modulators | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270508-A1 | GluR2 receptor modulators | GRM2, GRIK2, GRIN2A | TAAR1 376/4885APP 2410/4885TRPV1 390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.