SCHEMBL13256282

SCHEMBL13256282

CC(=O)CC(NC(=O)OCC1c2ccccc2-c2ccccc21)C(C)=O

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 4/20 0.54
KMT2A Q03164 2/20 0.51
MDM4 O15151 2/20 0.51
TP53 P04637 2/20 0.51
EPHX2 P34913 1/20 0.48
MDM2 Q00987 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13382807 1.00 CASP3 (0.54) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL14586400 1.00 CASP3 (0.54) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL12138344 0.91 CASP3 (0.58) CASP3KMT2AMDM4TP53MDM2
SCHEMBL14559793 0.91 CASP3 (0.58) CASP3KMT2AMDM4TP53MDM2
SCHEMBL5385200 0.91 CASP3 (0.58) CASP3KMT2AMDM4TP53MDM2
SCHEMBL13382806 0.91 CASP3 (0.61) CASP3KMT2AMDM4TP53MDM2
SCHEMBL7163160 0.91 CASP3 (0.61) CASP3KMT2AMDM4TP53MDM2
SCHEMBL26258624 0.90 CASP3 (0.52) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL10028351 0.90 KMT2A (0.53) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL13863441 0.90 KMT2A (0.53) CASP3KMT2AMDM4TP53EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8303956-B2 Glycosylated specificity exchangers CHRONTECH PHARMA AB (SE) 2012-11-06 US disclosed
US-20100183635-A1 GLYCOSYLATED SPECIFICITY EXCHANGERS TRIPEP AB (SE) 2010-07-22 US disclosed
US-20090305949-A1 GLYCOSYLATED SPECIFICITY EXCHANGER TRIPEP AB (SE) 2009-12-10 US disclosed
US-7534435-B2 Glycosylated specificity exchangers TRIPEP AB (SE) 2009-05-19 US disclosed
US-20090092631-A1 GLYCOSYLATED SPECIFICITY EXCHANGERS THAT INDUCE AN ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY (ADCC) RESPONSE TRIPEP AB (SE) 2009-04-09 US disclosed
US-7332166-B2 Glycosylated specificity exchangers TRIPEP AB (SE) 2008-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090305949-A1 GLYCOSYLATED SPECIFICITY EXCHANGER SLC17A5, ASGR1, SLC2A1 CASP3 4880/4885KMT2A 3283/4885MDM4 4771/4885
US-20090092631-A1 GLYCOSYLATED SPECIFICITY EXCHANGERS THAT INDUCE AN ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY (ADCC) RESPONSE SLC17A5, ASGR1, FCGR1A CASP3 4179/4885KMT2A 3756/4885MDM4 4458/4885
US-20100183635-A1 GLYCOSYLATED SPECIFICITY EXCHANGERS SLC17A5, ASGR1, SLC2A1 CASP3 4878/4885KMT2A 3462/4885MDM4 4738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.