Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL955586 | 0.80 | SMN1; SMN2 (0.40) | VCP | |
| SCHEMBL955587 | 0.80 | SMN1; SMN2 (0.40) | VCP | |
| SCHEMBL955033 | 0.79 | LMNA (0.34) | VCP | |
| SCHEMBL955032 | 0.79 | LMNA (0.34) | VCP | |
| SCHEMBL955082 | 0.69 | — | — | |
| SCHEMBL16937954 | 0.69 | KCNK13 (0.30) | — | |
| SCHEMBL955083 | 0.69 | — | — | |
| SCHEMBL13256709 | 0.67 | CDC7 (0.32) | — | |
| SCHEMBL952954 | 0.66 | TRPM8 (0.55) | — | |
| SCHEMBL952277 | 0.65 | SMN1; SMN2 (0.36) | VCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090716-A1 | HETEROARYLS AND THEIR USE AS PI3K INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-08-12 | — | — | WO | disclosed |