Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | TNF | P01375 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | GALR3 | O60755 | 2/20 | 0.57 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | HTR3A | P46098 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | HRH1 | P35367 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5199559 | 0.87 | TNF (0.65) | TP53HTTLMNAMEN1KMT2A | |
| SCHEMBL10353872 | 0.84 | RAB9A (0.50) | TP53HTTLMNAMEN1KMT2A | |
| SCHEMBL9537915 | 0.84 | RAB9A (0.65) | TP53HTTLMNAMEN1KMT2A | |
| SCHEMBL6833621 | 0.84 | TNF (0.81) | TP53HTTLMNAMEN1KMT2A | |
| SCHEMBL10353544 | 0.84 | SMN1; SMN2 (0.69) | TP53HTTLMNASMN1; SMN2MAPT | |
| SCHEMBL12116719 | 0.82 | TP53 (0.53) | TP53HTTLMNAMEN1KMT2A | |
| SCHEMBL5581775 | 0.81 | TP53 (0.91) | TP53HTTLMNAMEN1KMT2A | |
| SCHEMBL10353137 | 0.81 | KMT2A (0.71) | HTTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10353246 | 0.80 | TNF (0.52) | TP53LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8366932 | 0.80 | RAB9A (0.76) | TP53HTTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096830-A2 | METHOD TO TREAT PSORIASIS AND OTHER HYPERPROLIFERATIVE SKIN DISORDERS | CORNELL UNIVERSITY (US) | 2010-08-26 | — | — | WO | disclosed |