Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | NPY1R | P25929 | 1/20 | 0.54 |
| ▸ | NPY2R | P49146 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13257650 | 0.90 | LMNA (0.43) | ALDH1A1LMNAL3MBTL1NPY1RNPY2R | |
| SCHEMBL2561543 | 0.85 | ALDH1A1 (0.48) | ALDH1A1LMNAL3MBTL1NPY1RNPY2R | |
| SCHEMBL13257467 | 0.81 | ALDH1A1 (0.34) | ALDH1A1LMNAL3MBTL1NPY1RNPY2R | |
| SCHEMBL2565275 | 0.81 | PIK3CD (0.46) | ALDH1A1LMNAL3MBTL1NPY1RNPY2R | |
| SCHEMBL13258448 | 0.81 | JAK1 (0.37) | — | |
| SCHEMBL13266550 | 0.79 | MAPT (0.43) | ALDH1A1LMNAL3MBTL1NPY1RNPY2R | |
| SCHEMBL13257678 | 0.78 | PDE11A (0.43) | LMNAMAPK1ESR1ESR2MAPT | |
| SCHEMBL2567106 | 0.78 | PIK3CD (0.44) | ALDH1A1LMNAL3MBTL1NPY1RNPY2R | |
| SCHEMBL2566379 | 0.76 | PIK3CD (0.44) | ALDH1A1LMNAL3MBTL1NPY1RNPY2R | |
| SCHEMBL2561251 | 0.76 | PIK3CD (0.47) | ALDH1A1LMNAL3MBTL1NPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010087467-A1 | DELTA-5-DESATURASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-05 | — | — | WO | disclosed |