Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.43 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28481713 | 0.71 | ESR1 (0.58) | ESR1CES2CES1PTGS2CYP19A1 | |
| SCHEMBL5988427 | 0.71 | ESR1 (0.52) | ESR1CES2CES1PTGS2CYP19A1 | |
| Methyl Alcohol SCHEMBL28843164 | 0.70 | ESR1 (0.50) | ESR1CES2CES1PTGS2CYP19A1 | |
| SCHEMBL67982 | 0.69 | CES1 (0.53) | ESR1CES2CES1PTGS2TSHR | |
| Benzene SCHEMBL28326432 | 0.69 | CES1 (0.53) | ESR1CES2CES1PTGS2TSHR | |
| Ammonia Solution, Strong SCHEMBL28014231 | 0.69 | ESR1 (0.50) | ESR1CES2CES1PTGS2CYP19A1 | |
| SCHEMBL9806361 | 0.69 | ESR1 (0.77) | ESR1CES2CES1PTGS2CYP19A1 | |
| SCHEMBL124544 | 0.69 | ESR1 (0.41) | ESR1CES2CES1PTGS2CYP19A1 | |
| SCHEMBL13260438 | 0.68 | CES1 (0.42) | CES2CES1TSHRDAONAPRT | |
| SCHEMBL3854316 | 0.67 | ESR1 (0.48) | ESR1CES2CES1PTGS2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184887-A1 | HYBRID NANOPARTICLES | BASF SE (DE) | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184887-A1 | HYBRID NANOPARTICLES | RAB5IF, TTPA, PRNP | ESR1 1632/4885CES2 3765/4885CES1 3945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.