Ornithine Aketoglutarate

Ornithine Aketoglutarate

SCHEMBL1326163

NCCCC(N)C(=O)O.NCCCC(N)C(=O)O

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 2/20 0.86
ARG2 P78540 4/20 0.56
ARG1 P05089 3/20 0.56
CYP1A2 P05177 2/20 0.54
GRM8 O00222 1/20 0.54
GRM6 O15303 1/20 0.54
GRIN2D O15399 1/20 0.54
GRIN3B O60391 1/20 0.54
GRIK1 P39086 1/20 0.54
GRM5 P41594 1/20 0.54
GRIA1 P42261 1/20 0.54
GRIA2 P42262 1/20 0.54
GRIA3 P42263 1/20 0.54
SLC1A3 P43003 1/20 0.54
SLC1A2 P43004 1/20 0.54
SLC1A1 P43005 1/20 0.54
GRIA4 P48058 1/20 0.54
GRIN1 Q05586 1/20 0.54
GRIN2A Q12879 1/20 0.54
GRIK2 Q13002 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ornithine SCHEMBL30563013 1.00
D-Ornithine SCHEMBL1537220 1.00 GSR (0.86) GSRARG2ARG1CYP1A2GRM8
Ornithine SCHEMBL30695803 1.00
Ornithine SCHEMBL20362354 1.00
D-Ornithine SCHEMBL43724 1.00
Ornithine SCHEMBL30695804 1.00
Ornithine Aketoglutarate SCHEMBL42530 1.00 GSR (0.86) GSRARG2ARG1CYP1A2GRM8
Ornithine Aketoglutarate SCHEMBL8578 1.00
Ornithine SCHEMBL624782 1.00 GSR (0.86) GSRARG2ARG1CYP1A2GRM8
Ornithine SCHEMBL8579 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104193632-B A kind ofly prepare from biotechnology of enzymes the method that separates ornithine ornithine conversion fluid and form ornithine hydrochloride WUXI JINGHAI AMINO ACID CO., LTD. (CN) 2016-05-04 CN claimed
CN-104193632-A Method for separating L-ornithine from L-ornithine conversion solution prepared by using enzyme biotechnology and forming L-ornithine hydrochloride WUXI JINGHAI AMINO ACID CO LTD 2014-12-10 CN claimed
CN-117783317-A Intestinal flora polyamine metabolic activity detection system based on liquid chromatography-mass spectrometry 苏州大学 2024-03-29 CN disclosed
CN-114805487-B Polypeptide compound and application thereof 成都诺和晟泰生物科技有限公司 2024-03-12 CN disclosed
CN-113045625-B Polypeptides as somatostatin receptor agonists and uses thereof 成都诺和晟泰生物科技有限公司 2023-11-07 CN disclosed
CN-113072617-B Polypeptide compound and application thereof 成都诺和晟泰生物科技有限公司 2023-08-08 CN disclosed
CN-114805487-A Polypeptide compound and application thereof 成都诺和晟泰生物科技有限公司 2022-07-29 CN disclosed
CN-113072617-A Polypeptide compound and application thereof 成都诺和晟泰生物科技有限公司 2021-07-06 CN disclosed
CN-113045625-A Polypeptide as growth hormone secretagogue receptor agonist and application thereof 成都诺和晟泰生物科技有限公司 2021-06-29 CN disclosed
CN-110150760-A A kind of aerosol generation system 钟术光 2019-08-23 CN disclosed
US-20190214145-A1 Method and systems for creating and screening patient metabolite profile to diagnose current medical condition, diagnose current treatment state and recommend new treatment regimen KUREK ITZHAK (US) 2019-07-11 US disclosed
CN-104193632-B A kind ofly prepare from biotechnology of enzymes the method that separates ornithine ornithine conversion fluid and form ornithine hydrochloride WUXI JINGHAI AMINO ACID CO., LTD. (CN) 2016-05-04 CN disclosed
CN-104193632-B A kind ofly prepare from biotechnology of enzymes the method that separates ornithine ornithine conversion fluid and form ornithine hydrochloride WUXI JINGHAI AMINO ACID CO., LTD. (CN) 2016-05-04 CN disclosed
CN-104193632-B A kind ofly prepare from biotechnology of enzymes the method that separates ornithine ornithine conversion fluid and form ornithine hydrochloride WUXI JINGHAI AMINO ACID CO., LTD. (CN) 2016-05-04 CN disclosed
CN-104193632-A Method for separating L-ornithine from L-ornithine conversion solution prepared by using enzyme biotechnology and forming L-ornithine hydrochloride WUXI JINGHAI AMINO ACID CO LTD 2014-12-10 CN disclosed
US-20110274789-A1 ISOLATED LACTOBACILLUS PLANTARUM STRAIN INDUCIA DSM 21379 AS PROBIOTIC THAT ENHANCES NATURAL IMMUNITY AND FOOD PRODUCTS AND MEDICINAL PREPARATIONS COMPRISING IT TERVISLIKU PIIMA BIOTEHNOLOOGIATE ARENDUSKESKUS OU (BIO-COMPETENCE CENTRE OF HEALTHY DAIRY PRODUCTS) (EE) 2011-11-10 US disclosed
EP-2288360-A1 ISOLATED LACTOBACILLUS PLANTARUM STRAIN INDUCIA DSM 21379 AS PROBIOTIC THAT ENHANCES NATURAL IMMUNITY AND FOOD PRODUCTS AND MEDICINAL PREPARATIONS COMPRISING IT Oü Tervisliku Piima Biotehnoloogiate Arenduskeskus (EE) 2011-03-02 EP disclosed
CN-100399948-C Beverage containing amino acid and method of diminishing bitterness of amino acid KYOWA HAKKO KOGYO KK (JP) 2008-07-09 CN disclosed
CN-1719987-A Beverage containing amino acid and method of diminishing bitterness of amino acid KYOWA HAKKO KOGYO KK (JP) 2006-01-11 CN disclosed
US-4279917-A Amino acid solution for intravenous nutrition AJINOMOTO COMPANY, INCORPORATED (JP) 1981-07-21 US disclosed