Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.86 |
| ▸ | ARG2 | P78540 | 4/20 | 0.56 |
| ▸ | ARG1 | P05089 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | GRM8 | O00222 | 1/20 | 0.54 |
| ▸ | GRM6 | O15303 | 1/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.54 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.54 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.54 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.54 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.54 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.54 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.54 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ornithine SCHEMBL30563013 | 1.00 | — | — | |
| D-Ornithine SCHEMBL1537220 | 1.00 | GSR (0.86) | GSRARG2ARG1CYP1A2GRM8 | |
| Ornithine SCHEMBL30695803 | 1.00 | — | — | |
| Ornithine SCHEMBL20362354 | 1.00 | — | — | |
| Ornithine Aketoglutarate SCHEMBL1326163 | 1.00 | GSR (0.86) | GSRARG2ARG1CYP1A2GRM8 | |
| D-Ornithine SCHEMBL43724 | 1.00 | — | — | |
| Ornithine SCHEMBL30695804 | 1.00 | — | — | |
| Ornithine Aketoglutarate SCHEMBL8578 | 1.00 | — | — | |
| Ornithine SCHEMBL624782 | 1.00 | GSR (0.86) | GSRARG2ARG1CYP1A2GRM8 | |
| Ornithine SCHEMBL8579 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110286915-A1 | Nanocarriers for Drug Delivery | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-11-24 | — | — | US | claimed |
| EP-2344134-A2 | NANOCARRIERS FOR DRUG DELIVERY | The Regents of the University of California (US) | 2011-07-20 | — | — | EP | claimed |
| US-8541184-B2 | Screening for neurotoxic amino acid associated with neurological disorders | THE INSTITUTE FOR ETHNOMEDICINE (US) | 2013-09-24 | — | — | US | disclosed |
| EP-2449488-A1 | METHOD FOR NORMALIZATION IN METABOLOMICS ANALYSIS METHODS WITH ENDOGENOUS REFERENCE METABOLITES | BIOCRATES Life Sciences AG (AT) | 2012-05-09 | — | — | EP | disclosed |
| EP-2430105-A1 | AQUEOUS BINDER SYSTEM COMPRISING EPOXY-FUNCTIONAL AND CARBOXYL-FUNCTIONAL COMPONENTS, A PROCESS FOR THEIR MANUFACTURE, AND A METHOD OF USE THEREOF | Cytec Austria GmbH (AT) | 2012-03-21 | — | — | EP | disclosed |
| US-8119780-B2 | Chitosan-derivative compounds and methods of controlling microbial populations | SYNEDGEN, INC. (US) | 2012-02-21 | — | — | US | disclosed |
| US-20120028927-A1 | Novel Triazene Compounds For The Treatment Of Cancer | TRIN THERAPEUTICS GMBH (DE) | 2012-02-02 | — | — | US | disclosed |
| US-20110286921-A1 | 18F-LABELLED FOLATES AS PET RADIOTRACERS | Merck & Cie (CH) | 2011-11-24 | — | — | US | disclosed |
| US-20110286915-A1 | Nanocarriers for Drug Delivery | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-11-24 | — | — | US | disclosed |
| EP-2387409-A1 | CHITOSAN DERIVATIVES ALONE OR IN COMBINATION FOR THE TREATMENT OF MDR MICROBIAL INFECTIONS | Synedgen, Inc. (US) | 2011-11-23 | — | — | EP | disclosed |
| US-8038990-B2 | Compositions and methods for the prevention and removal of biofilms on inert and biological surfaces | THE OHIO STATE UNIVERSITY (US) | 2011-10-18 | — | — | US | disclosed |
| WO-2011028967-A1 | METHODS AND COMPOSITIONS FOR DISRUPTING BIOFILM UTILIZING CHITOSAN-DERIVATIVE COMPOUNDS | SYNEDGEN INC. (US) | 2011-03-10 | — | — | WO | disclosed |
| US-7901895-B2 | Screening environmental samples such as food, water for beta-N-methylamino-L-alanine (BMAA) associated with risk of nervous system disorders such as dementia, amyotrophic lateral sclerosis | THE INSTITUTE FOR ETHNOMEDICINE (US) | 2011-03-08 | — | — | US | disclosed |
| US-20110041210-A1 | Plants Having Enhanced Yield-Related Traits and a Method for Making the Same | BASF PLANT SCIENCE GMBH | 2011-02-17 | — | — | US | disclosed |
| US-20110028596-A1 | RUBBER COMPOSITION FOR COATING A STEEL WIRE MATERIAL | THE YOKOHAMA RUBBER CO., LTD | 2011-02-03 | — | — | US | disclosed |
| WO-2011000753-A1 | METHOD FOR NORMALIZATION IN METABOLOMICS ANALYSIS METHODS WITH ENDOGENOUS REFERENCE METABOLITES | BIOCRATES LIFE SCIENCES AG (AT) | 2011-01-06 | — | — | WO | disclosed |
| EP-2268820-A1 | PLANTS HAVING ENHANCED YIELD-RELATED TRAITS AND A METHOD FOR MAKING THE SAME | BASF Plant Science GmbH (DE) | 2011-01-05 | — | — | EP | disclosed |
| WO-1997016407-A1 | BETA-AMINO ESTER COMPOUNDS OF PERFUME ALCOHOLS | THE PROCTER & GAMBLE COMPANY (US) | 1997-05-09 | — | — | WO | disclosed |
| EP-0771785-A1 | Beta-amino ester compounds of perfume alcohols and their use in cleaning or laundry compositions | THE PROCTER & GAMBLE COMPANY (US) | 1997-05-07 | — | — | EP | disclosed |
| WO-1996023490-A9 | FORMULATIONS AND METHODS FOR REDUCING SKIN IRRITATION | — | 1996-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110286921-A1 | 18F-LABELLED FOLATES AS PET RADIOTRACERS | FOLR1, FOLR2, SLC19A1 | GSR 360/4885ARG2 1559/4885ARG1 1658/4885 |
| US-20110286915-A1 | Nanocarriers for Drug Delivery | CLTA, EPCAM, EGFR | GSR 1966/4885ARG2 2821/4885ARG1 3516/4885 |
| US-20120028927-A1 | Novel Triazene Compounds For The Treatment Of Cancer | KRAS, TP53, VHL | GSR 860/4885ARG2 2268/4885ARG1 3926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.