Ornithine

Ornithine

SCHEMBL624782

NCCC[C@H](N)C(=O)O.NCCC[C@H](N)C(=O)O

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 2/20 0.86
ARG2 P78540 4/20 0.56
ARG1 P05089 3/20 0.56
CYP1A2 P05177 2/20 0.54
GRM8 O00222 1/20 0.54
GRM6 O15303 1/20 0.54
GRIN2D O15399 1/20 0.54
GRIN3B O60391 1/20 0.54
GRIK1 P39086 1/20 0.54
GRM5 P41594 1/20 0.54
GRIA1 P42261 1/20 0.54
GRIA2 P42262 1/20 0.54
GRIA3 P42263 1/20 0.54
SLC1A3 P43003 1/20 0.54
SLC1A2 P43004 1/20 0.54
SLC1A1 P43005 1/20 0.54
GRIA4 P48058 1/20 0.54
GRIN1 Q05586 1/20 0.54
GRIN2A Q12879 1/20 0.54
GRIK2 Q13002 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ornithine SCHEMBL30563013 1.00
D-Ornithine SCHEMBL1537220 1.00 GSR (0.86) GSRARG2ARG1CYP1A2GRM8
Ornithine SCHEMBL30695803 1.00
Ornithine SCHEMBL20362354 1.00
Ornithine Aketoglutarate SCHEMBL1326163 1.00 GSR (0.86) GSRARG2ARG1CYP1A2GRM8
D-Ornithine SCHEMBL43724 1.00
Ornithine SCHEMBL30695804 1.00
Ornithine Aketoglutarate SCHEMBL42530 1.00 GSR (0.86) GSRARG2ARG1CYP1A2GRM8
Ornithine Aketoglutarate SCHEMBL8578 1.00
Ornithine SCHEMBL8579 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104193632-B A kind ofly prepare from biotechnology of enzymes the method that separates ornithine ornithine conversion fluid and form ornithine hydrochloride WUXI JINGHAI AMINO ACID CO., LTD. (CN) 2016-05-04 CN claimed
CN-104193632-A Method for separating L-ornithine from L-ornithine conversion solution prepared by using enzyme biotechnology and forming L-ornithine hydrochloride WUXI JINGHAI AMINO ACID CO LTD 2014-12-10 CN claimed
US-20110287479-A1 PROTEASE CATALYZED IN SITU END CAPPING OF OLIGOPEPTIDES IN AQUEOUS MEDIA POLYTECHNIC INSTITUTE OF NEW YORK UNIVERSITY (US) 2011-11-24 US claimed
US-20190214145-A1 Method and systems for creating and screening patient metabolite profile to diagnose current medical condition, diagnose current treatment state and recommend new treatment regimen KUREK ITZHAK (US) 2019-07-11 US disclosed
CN-104193632-B A kind ofly prepare from biotechnology of enzymes the method that separates ornithine ornithine conversion fluid and form ornithine hydrochloride WUXI JINGHAI AMINO ACID CO., LTD. (CN) 2016-05-04 CN disclosed
CN-104193632-B A kind ofly prepare from biotechnology of enzymes the method that separates ornithine ornithine conversion fluid and form ornithine hydrochloride WUXI JINGHAI AMINO ACID CO., LTD. (CN) 2016-05-04 CN disclosed
CN-104193632-B A kind ofly prepare from biotechnology of enzymes the method that separates ornithine ornithine conversion fluid and form ornithine hydrochloride WUXI JINGHAI AMINO ACID CO., LTD. (CN) 2016-05-04 CN disclosed
CN-104193632-A Method for separating L-ornithine from L-ornithine conversion solution prepared by using enzyme biotechnology and forming L-ornithine hydrochloride WUXI JINGHAI AMINO ACID CO LTD 2014-12-10 CN disclosed
EP-2449488-A1 METHOD FOR NORMALIZATION IN METABOLOMICS ANALYSIS METHODS WITH ENDOGENOUS REFERENCE METABOLITES BIOCRATES Life Sciences AG (AT) 2012-05-09 EP disclosed
US-20110287479-A1 PROTEASE CATALYZED IN SITU END CAPPING OF OLIGOPEPTIDES IN AQUEOUS MEDIA POLYTECHNIC INSTITUTE OF NEW YORK UNIVERSITY (US) 2011-11-24 US disclosed
US-20110274789-A1 ISOLATED LACTOBACILLUS PLANTARUM STRAIN INDUCIA DSM 21379 AS PROBIOTIC THAT ENHANCES NATURAL IMMUNITY AND FOOD PRODUCTS AND MEDICINAL PREPARATIONS COMPRISING IT TERVISLIKU PIIMA BIOTEHNOLOOGIATE ARENDUSKESKUS OU (BIO-COMPETENCE CENTRE OF HEALTHY DAIRY PRODUCTS) (EE) 2011-11-10 US disclosed
EP-2288360-A1 ISOLATED LACTOBACILLUS PLANTARUM STRAIN INDUCIA DSM 21379 AS PROBIOTIC THAT ENHANCES NATURAL IMMUNITY AND FOOD PRODUCTS AND MEDICINAL PREPARATIONS COMPRISING IT Oü Tervisliku Piima Biotehnoloogiate Arenduskeskus (EE) 2011-03-02 EP disclosed
WO-2011000753-A1 METHOD FOR NORMALIZATION IN METABOLOMICS ANALYSIS METHODS WITH ENDOGENOUS REFERENCE METABOLITES BIOCRATES LIFE SCIENCES AG (AT) 2011-01-06 WO disclosed
CN-100399948-C Beverage containing amino acid and method of diminishing bitterness of amino acid KYOWA HAKKO KOGYO KK (JP) 2008-07-09 CN disclosed
CN-1719987-A Beverage containing amino acid and method of diminishing bitterness of amino acid KYOWA HAKKO KOGYO KK (JP) 2006-01-11 CN disclosed
WO-1996023490-A9 FORMULATIONS AND METHODS FOR REDUCING SKIN IRRITATION 1996-12-27 WO disclosed
US-4279917-A Amino acid solution for intravenous nutrition AJINOMOTO COMPANY, INCORPORATED (JP) 1981-07-21 US disclosed