Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TSSK1B | Q9BXA7 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6631891 | 0.77 | MEN1 (0.46) | ALDH1A1MEN1KMT2AMAPK1POLB | |
| SCHEMBL6630982 | 0.76 | MEN1 (0.44) | ALDH1A1HTTMEN1KMT2AMAPK1 | |
| SCHEMBL6630986 | 0.76 | MEN1 (0.47) | ALDH1A1HTTMEN1KMT2AKDM4E | |
| SCHEMBL7170109 | 0.74 | ALDH1A1 (0.56) | ALDH1A1HTTMEN1KMT2AKDM4E | |
| SCHEMBL7103060 | 0.72 | POLB (0.46) | ALDH1A1MEN1KMT2AMAPK1POLB | |
| SCHEMBL7098427 | 0.72 | MEN1 (0.46) | ALDH1A1MEN1KMT2AMAPK1POLB | |
| 7,8-Dihydrocalanolide B SCHEMBL29623986 | 0.72 | APAF1 (0.66) | ALDH1A1MEN1KMT2AMAPK1POLB | |
| SCHEMBL7097929 | 0.72 | MEN1 (0.44) | ALDH1A1MEN1KMT2AKDM4EMAPK1 | |
| SCHEMBL13261760 | 0.72 | MEN1 (0.44) | ALDH1A1MEN1KMT2AMAPK1POLB | |
| 7,8-Dihydrocalanolide B SCHEMBL29517130 | 0.72 | APAF1 (0.66) | ALDH1A1MEN1KMT2AMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2216335-A1 | TETRIACYCLODIPYRANYL COUMARINS AND THE ANTI-HIV AND ANTI-TUBERCULOSIS USES THEREOF | Institute of Mataria Medica, Chinese Academy of Medical Sciences (CN) | 2010-08-11 | — | — | EP | disclosed |