Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.64 |
| ▸ | MAOA | P21397 | 1/20 | 0.64 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.54 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13792894 | 0.81 | MCHR1 (0.56) | KDM1AMAOA | |
| SCHEMBL6875610 | 0.81 | KDM1A (0.46) | KDM1AMAOADPP8DPP7KMT2A | |
| SCHEMBL6875616 | 0.81 | KDM1A (0.46) | KDM1AMAOADPP8DPP7KMT2A | |
| SCHEMBL6877152 | 0.80 | MCHR1 (0.51) | KDM1AMAOADPP8DPP7KMT2A | |
| SCHEMBL6877157 | 0.80 | MCHR1 (0.51) | KDM1AMAOADPP8DPP7KMT2A | |
| SCHEMBL1254854 | 0.80 | KMT2A (0.61) | KDM1AMAOAKMT2APOLBSMN1; SMN2 | |
| SCHEMBL2755998 | 0.79 | KDM1A (1.00) | KDM1AMAOAKMT2APOLB | |
| SCHEMBL237668 | 0.79 | KDM1A (1.00) | KDM1AMAOAKMT2APOLB | |
| SCHEMBL237667 | 0.79 | KDM1A (1.00) | KDM1AMAOAKMT2APOLB | |
| SCHEMBL6873525 | 0.78 | KDM1A (0.43) | KDM1AMAOADPP8DPP7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010084160-A1 | PHENYLCYCLOPROPYLAMINE DERIVATIVES AND THEIR MEDICAL USE | ORYZON GENOMICS S.A. (ES) | 2010-07-29 | — | — | WO | disclosed |