Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877157 | 1.00 | MCHR1 (0.51) | MCHR1KDM1AMAOAAPPBCHE | |
| SCHEMBL6878019 | 0.91 | MCHR1 (0.53) | MCHR1KDM1AMAOAAPPBCHE | |
| SCHEMBL6878027 | 0.91 | MCHR1 (0.53) | MCHR1KDM1AMAOAAPPBCHE | |
| SCHEMBL6877318 | 0.89 | MCHR1 (0.44) | MCHR1KDM1AMAOAAPPBCHE | |
| SCHEMBL6877323 | 0.89 | MCHR1 (0.44) | MCHR1KDM1AMAOAAPPBCHE | |
| SCHEMBL6873635 | 0.86 | MCHR1 (0.51) | MCHR1KDM1AMAOAAPPBCHE | |
| SCHEMBL6873630 | 0.86 | MCHR1 (0.51) | MCHR1KDM1AMAOAAPPBCHE | |
| SCHEMBL6879016 | 0.86 | MCHR1 (0.51) | MCHR1APPBCHEACHEKMT2A | |
| SCHEMBL6879011 | 0.86 | MCHR1 (0.51) | MCHR1APPBCHEACHEKMT2A | |
| SCHEMBL6877379 | 0.84 | MCHR1 (0.50) | MCHR1APPBCHEACHEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |