Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
| ▸ | GRM8 | O00222 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16856007 | 0.90 | GRM8 (0.42) | PTGS2PTGS1TUBB1GRM8CYP1A2 | |
| SCHEMBL802792 | 0.87 | ACHE (0.42) | PTGS2PTGS1GRM8CYP1A2CYP2C9 | |
| SCHEMBL3769995 | 0.86 | TUBB1 (0.44) | TUBB1GRM8CYP1A2CYP2C9TACR1 | |
| SCHEMBL16848662 | 0.85 | ACHE (0.41) | PTGS2PTGS1GRM8CYP1A2CYP2C9 | |
| SCHEMBL16852368 | 0.84 | PTGS2 (0.49) | PTGS2PTGS1TUBB1CYP1A2CYP2C9 | |
| SCHEMBL803253 | 0.84 | PTGS2 (0.38) | PTGS2PTGS1 | |
| SCHEMBL14015537 | 0.83 | ABL1 (0.43) | PTGS2CYP1A2CYP2C9 | |
| SCHEMBL17775109 | 0.83 | ABL1 (0.43) | PTGS2CYP1A2CYP2C9 | |
| SCHEMBL13653996 | 0.82 | FGFR2 (0.40) | CYP1A2 | |
| SCHEMBL15681343 | 0.81 | CHEK1 (0.49) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206695-A1 | TETRA- OR PENTA-CYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | Chisso Corporation (JP) | 2010-07-14 | — | — | EP | disclosed |