Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL201854 | 0.85 | EPHX2 (0.54) | EPHX2NR1H4NAMPTCYP2C9MAPK8 | |
| SCHEMBL5445398 | 0.84 | EPHX2 (0.59) | EPHX2NR1H4NAMPTCA1CA2 | |
| SCHEMBL3930626 | 0.82 | EPHX2 (0.57) | EPHX2NR1H4NAMPTCYP2C9MAPK8 | |
| SCHEMBL4899305 | 0.80 | EPHX2 (0.59) | EPHX2NR1H4NAMPTCYP2C9CHRM4 | |
| SCHEMBL28255002 | 0.79 | CYP2C9 (0.58) | EPHX2NR1H4NAMPTCYP2C9MAPK8 | |
| SCHEMBL935250 | 0.77 | EPHX2 (0.56) | EPHX2NR1H4NAMPTCA1CA2 | |
| SCHEMBL12049672 | 0.77 | EPHX2 (0.56) | EPHX2NR1H4NAMPTCYP2C9CHRM4 | |
| SCHEMBL4573368 | 0.77 | EPHX2 (0.47) | EPHX2NR1H4CA1CA2ENPP2 | |
| SCHEMBL14039212 | 0.77 | KMT2A (0.63) | ALDH1A1GAA | |
| SCHEMBL14368081 | 0.76 | ERCC1 (0.55) | EPHX2NR1H4NAMPTCYP2C9MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100168112-A1 | 2-Substituted and 4-substituted aryl nitrone compounds | RENOVIS, INC. | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168112-A1 | 2-Substituted and 4-substituted aryl nitrone compounds | CXCR2, CCL5, CCL2 | EPHX2 1379/4885NR1H4 572/4885NAMPT 506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.