SCHEMBL13263448

SCHEMBL13263448

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nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CTSK P43235 7/20 0.48
CTSS P25774 5/20 0.48
CTSL P07711 2/20 0.48
CTSB P07858 1/20 0.48
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CYP2D6 P10635 1/20 0.45
REN P00797 3/20 0.44
CAPN1 P07384 1/20 0.42
AAK1 Q2M2I8 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2632701 0.88 CTSK (0.60) CTSKCTSSCTSLCTSBCA1
SCHEMBL14152879 0.88 CTSK (0.60) CTSKCTSSCTSLCTSBCA1
SCHEMBL14167474 0.85 CA1 (0.47) CTSKCTSSCTSLCTSBCA1
SCHEMBL19651564 0.81 CYP1A2 (0.43) CTSKCTSSCTSLCTSBCA1
SCHEMBL26206773 0.81 CTSK (0.46) CTSKCTSSCTSLCTSBCA1
SCHEMBL18892598 0.81 CTSK (0.58) CTSKCTSSCTSLCTSBCA1
SCHEMBL16162484 0.81 CTSK (0.47) CTSKCTSSCTSLCTSBCA1
SCHEMBL1534907 0.81 CTSK (0.47) CTSKCTSSCTSLCTSBCA1
SCHEMBL18925259 0.81 CTSK (0.58) CTSKCTSSCTSLCTSBCA1
SCHEMBL5532831 0.81 CTSK (0.58) CTSKCTSSCTSLCTSBCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010077798-A2 STEREOSELECTIVE SYNTHESIS OF PIPERIDINE DERIVATIVES TAIGEN BIOTECHNOLOGY CO., LTD. (TW) 2010-07-08 WO disclosed
US-20100152452-A1 STEREOSELECTIVE SYNTHESIS OF PIPERIDINE DERIVATIVES TAIGEN BIOTECHNOLOGY CO., LTD. (TW) 2010-06-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100152452-A1 STEREOSELECTIVE SYNTHESIS OF PIPERIDINE DERIVATIVES DHPS, AZI2, DPYD CTSK 4224/4885CTSS 3427/4885CTSL 4585/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.