Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.65 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.57 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.57 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 5/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10771747 | 0.78 | AXL (0.67) | AXLLOXL2CA2PDGFRBPDGFRA | |
| SCHEMBL74023 | 0.78 | AXL (1.00) | AXLLOXL2CA2PDGFRBPDGFRA | |
| SCHEMBL30235444 | 0.78 | AXL (1.00) | AXLLOXL2CA2PDGFRBPDGFRA | |
| SCHEMBL12778113 | 0.77 | AXL (0.65) | AXLLOXL2CA2PDGFRBPDGFRA | |
| SCHEMBL28018748 | 0.77 | AXL (0.65) | AXLLOXL2CA2PDGFRBPDGFRA | |
| SCHEMBL9296104 | 0.77 | AXL (0.65) | AXLLOXL2CA2PDGFRBPDGFRA | |
| SCHEMBL7965312 | 0.77 | AXL (0.65) | AXLLOXL2CA2PDGFRBPDGFRA | |
| SCHEMBL23419191 | 0.77 | KDM4E (0.57) | KDM4EKMT2AMAPTNPC1RAB9A | |
| SCHEMBL3507809 | 0.77 | LOXL2 (1.00) | AXLLOXL2CA2PDGFRBPDGFRA | |
| SCHEMBL867547 | 0.76 | LOXL2 (0.75) | AXLLOXL2CA2PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022093729-A1 | REPLICATION-DEFECTIVE VACCINES AND USES THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2022-05-05 | — | — | WO | disclosed |
| CN-108440496-B | A method of preparing 2- aminoindole derivatives | 苏州大学 | 2019-09-10 | — | — | CN | disclosed |
| CN-108440496-A | A method of preparing 2- aminoindole derivatives | 苏州大学 | 2018-08-24 | — | — | CN | disclosed |
| WO-2010074244-A1 | ISOQUINOLINE DERIVATIVE | 大正製薬株式会社 (JP) | 2010-07-01 | — | — | WO | disclosed |