Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 14/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13264199 | 0.89 | GPR119 (0.38) | GCK | |
| SCHEMBL13264141 | 0.89 | GCK (0.34) | GCK | |
| SCHEMBL13264305 | 0.88 | TDO2 (0.31) | — | |
| SCHEMBL422149 | 0.88 | GCK (0.46) | GCK | |
| SCHEMBL13264191 | 0.88 | GCK (0.33) | GCK | |
| SCHEMBL425620 | 0.86 | GCK (0.41) | GCK | |
| SCHEMBL12259638 | 0.84 | GCK (0.45) | GCK | |
| SCHEMBL13263980 | 0.83 | GCK (0.33) | GCK | |
| SCHEMBL13264139 | 0.81 | GCK (0.39) | GCK | |
| SCHEMBL423373 | 0.81 | GCK (0.44) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010082601-A1 | NOVEL 2,5-DISUBSTITUTED PYRROLE DERIVATIVE | 第一三共株式会社 (JP) | 2010-07-22 | — | — | WO | disclosed |