Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
| ▸ | GABRE | P78334 | 1/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.31 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.31 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2839580 | 0.80 | GABRB3 (0.47) | GABRPGABRDNR1I2LMNACYP3A4 | |
| SCHEMBL13264754 | 0.78 | GABRB3 (0.36) | GABRPGABRDNR1I2LMNACYP3A4 | |
| SCHEMBL16864090 | 0.77 | GABRP (0.46) | GABRPGABRDNR1I2LMNACYP3A4 | |
| SCHEMBL2839181 | 0.73 | GABRB3 (0.46) | GABRPGABRDNR1I2LMNACYP3A4 | |
| SCHEMBL12315444 | 0.71 | GABRP (0.54) | GABRPGABRDNR1I2LMNACYP3A4 | |
| SCHEMBL2842449 | 0.70 | GABRB3 (0.48) | GABRPGABRDNR1I2LMNACYP3A4 | |
| SCHEMBL15887486 | 0.70 | GABRP (0.46) | GABRPGABRDNR1I2LMNACYP3A4 | |
| SCHEMBL2837055 | 0.70 | GABRB3 (0.50) | GABRPGABRDNR1I2LMNACYP3A4 | |
| SCHEMBL6055918 | 0.68 | GABRB3 (0.53) | GABRPGABRDNR1I2LMNACYP3A4 | |
| SCHEMBL2836815 | 0.68 | GABRP (0.35) | GABRPGABRDNR1I2LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759381-B2 | 1-aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof | AVENTIS AGRICULTURE (FR) | 2010-07-20 | — | — | US | disclosed |