SCHEMBL1326522

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1326713	0.83	BCL2A1 (0.46)	SLC6A4SLC6A2AOC3HSD11B1SLC6A3
	SCHEMBL493690	0.83	AOC3 (0.38)	SLC6A4CHRM1SLC6A2AOC3SLC6A3
	SCHEMBL3590453	0.83	SLC6A4 (0.40)	SLC6A4CHRM1SLC6A2AOC3SLC6A3
	SCHEMBL1327227	0.83	OPRM1 (0.41)	SLC6A4SLC6A3OPRM1KDRHTR2A
	SCHEMBL1326885	0.83	AOC3 (0.37)	SLC6A4CHRM1SLC6A2AOC3SLC6A3
	SCHEMBL1326919	0.81	SLC6A4 (0.45)	SLC6A4SLC6A2AOC3SLC6A3OPRM1
	SCHEMBL644291	0.80	LMNA (0.40)	AOC3
	SCHEMBL1327560	0.80	ESR2 (0.36)	SLC6A4CHRM1SLC6A2AOC3SLC6A3
	SCHEMBL493315	0.80	AOC3 (0.37)	SLC6A4CHRM1SLC6A2AOC3SLC6A3
	SCHEMBL493325	0.80	CHRM1 (0.35)	SLC6A4CHRM1SLC6A2AOC3SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.