Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.55 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12202096 | 0.81 | CYP4F2 (0.39) | CYP4F2CYP4A11ALDH1A1GAALMNA | |
| SCHEMBL13265232 | 0.80 | CYP4F2 (0.40) | CYP4F2CYP4A11ALDH1A1GAALMNA | |
| SCHEMBL10134594 | 0.80 | CYP4F2 (0.49) | CYP4F2CYP4A11ALDH1A1GAAKDM4E | |
| SCHEMBL69660 | 0.77 | CYP4F2 (0.86) | CYP4F2CYP4A11ALDH1A1GAALMNA | |
| SCHEMBL12203061 | 0.76 | MEN1 (0.46) | CYP4F2CYP4A11ALDH1A1LMNACYP2D6 | |
| SCHEMBL17226942 | 0.76 | MEN1 (0.46) | CYP4F2CYP4A11ALDH1A1LMNACYP2D6 | |
| SCHEMBL20030391 | 0.74 | CYP4F2 (0.61) | CYP4F2CYP4A11ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL28008696 | 0.74 | CYP4F2 (0.81) | CYP4F2CYP4A11ALDH1A1GAALMNA | |
| SCHEMBL11587953 | 0.73 | CYP4F2 (0.73) | CYP4F2CYP4A11ALDH1A1GAALMNA | |
| SCHEMBL1511313 | 0.73 | CYP4F2 (0.69) | CYP4F2CYP4A11ALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374794-B1 | CYCLIC AMINE COMPOUNDS | DAIICHI SANKYO CO LTD (JP) | 2015-11-04 | — | — | EP | disclosed |
| WO-2010074088-A1 | CYCLIC AMINE COMPOUNDS | 第一三共株式会社 (JP) | 2010-07-01 | — | — | WO | disclosed |