Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6800028 | 0.87 | CYP4F2 (0.39) | CYP4F2CYP4A11PKMALDH1A1GAA | |
| SCHEMBL10134625 | 0.81 | CYP4F2 (0.36) | CYP4F2CYP4A11PKMALDH1A1GAA | |
| SCHEMBL13265233 | 0.80 | CYP4F2 (0.55) | CYP4F2CYP4A11ALDH1A1GAALMNA | |
| SCHEMBL12202096 | 0.79 | CYP4F2 (0.39) | CYP4F2CYP4A11ALDH1A1GAALMNA | |
| SCHEMBL10134623 | 0.75 | CYP4F2 (0.36) | CYP4F2CYP4A11PKMALDH1A1GAA | |
| SCHEMBL12202099 | 0.73 | CYP4F2 (0.40) | CYP4F2CYP4A11ALDH1A1GAALMNA | |
| SCHEMBL13265175 | 0.72 | CYP4F2 (0.42) | CYP4F2CYP4A11ALDH1A1GAALMNA | |
| SCHEMBL31295082 | 0.71 | CYP4F2 (0.48) | CYP4F2CYP4A11PKMALDH1A1GAA | |
| SCHEMBL13263963 | 0.71 | CYP4F2 (0.40) | CYP4F2CYP4A11ALDH1A1GAALMNA | |
| SCHEMBL6745216 | 0.71 | CYP4F2 (0.36) | CYP4F2CYP4A11PKMALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074088-A1 | CYCLIC AMINE COMPOUNDS | 第一三共株式会社 (JP) | 2010-07-01 | — | — | WO | disclosed |