Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2E1 | Q9Y466 | 5/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.53 |
| ▸ | HTR2B | P41595 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.53 |
| ▸ | HTR2C | P28335 | 3/20 | 0.53 |
| ▸ | HTR6 | P50406 | 3/20 | 0.53 |
| ▸ | HTR1B | P28222 | 3/20 | 0.53 |
| ▸ | SCN1A | P35498 | 2/20 | 0.53 |
| ▸ | SLC10A1 | Q14973 | 2/20 | 0.53 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.53 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13077341 | 0.88 | NR2E1 (0.56) | NR2E1ADRB2ADRB1CYP2D6SIGMAR1 | |
| SCHEMBL14107149 | 0.87 | NR2E1 (0.63) | NR2E1ADRB2ADRB1CYP2D6SIGMAR1 | |
| SCHEMBL22354579 | 0.86 | NR2E1 (0.67) | NR2E1ADRB2ADRB1CYP2D6SIGMAR1 | |
| SCHEMBL7770898 | 0.85 | NR2E1 (0.60) | NR2E1ADRB2ADRB1CYP2D6SIGMAR1 | |
| SCHEMBL11025259 | 0.85 | NR2E1 (0.60) | NR2E1ADRB2ADRB1CYP2D6SIGMAR1 | |
| SCHEMBL3259801 | 0.85 | NR2E1 (0.55) | NR2E1ADRB2ADRB1CYP2D6SIGMAR1 | |
| SCHEMBL13077340 | 0.83 | NR2E1 (0.39) | NR2E1ADRB2ADRB1CYP2D6SIGMAR1 | |
| SCHEMBL25587771 | 0.82 | NR2E1 (0.68) | NR2E1ADRB2ADRB1CYP2D6SIGMAR1 | |
| SCHEMBL2796170 | 0.80 | NR2E1 (0.54) | NR2E1ADRB2ADRB1CYP2D6SIGMAR1 | |
| SCHEMBL13077335 | 0.80 | NR2E1 (0.56) | NR2E1ADRB2ADRB1CYP2D6SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759392-B2 | Pharmaceutical compounds | NICOX S.A. (FR) | 2010-07-20 | — | — | US | disclosed |
| US-20090170941-A1 | Pharmaceutical Compounds | NICOX S.A. (FR) | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170941-A1 | Pharmaceutical Compounds | NR0B2, NR0B1, CYP11B2 | NR2E1 45/4885ADRB2 16/4885ADRB1 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.