Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | ATM | Q13315 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1754956 | 0.77 | MEN1 (0.39) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL18685198 | 0.72 | SMN1; SMN2 (0.41) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL20355964 | 0.72 | HTT (0.46) | ALDH1A1MAPTHPGDKDM4EHSD17B10 | |
| SCHEMBL1754969 | 0.71 | MEN1 (0.37) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL18680081 | 0.71 | SMN1; SMN2 (0.43) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL13056570 | 0.70 | NQO2 (0.46) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL13056575 | 0.70 | SMN1; SMN2 (0.47) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL13056572 | 0.70 | ALDH1A1 (0.37) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL23308032 | 0.70 | SMN1; SMN2 (0.43) | ALDH1A1MAPTHPGDATMLMNA | |
| SCHEMBL13056574 | 0.69 | SMN1; SMN2 (0.48) | ALDH1A1HPGDLMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184087-A1 | Haptens, hapten conjugates, compositions thereof and method for their preparation and use | VENTANA MEDICAL SYSTEMS, INC. | 2010-07-22 | — | — | US | disclosed |