Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | ACR | P10323 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1754956 | 0.81 | MEN1 (0.39) | MEN1KMT2ASMN1; SMN2KDM4EGLA | |
| SCHEMBL13268043 | 0.71 | MEN1 (0.39) | MEN1KMT2ASMN1; SMN2KDM4EGLA | |
| SCHEMBL20355964 | 0.71 | HTT (0.46) | SMN1; SMN2KDM4EMAPTMTNR1AMTNR1B | |
| SCHEMBL18685198 | 0.69 | SMN1; SMN2 (0.41) | MEN1KMT2ASMN1; SMN2KDM4EGLA | |
| SCHEMBL13056570 | 0.69 | NQO2 (0.46) | MEN1KMT2ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL18680081 | 0.68 | SMN1; SMN2 (0.43) | MEN1KMT2ASMN1; SMN2KDM4EGLA | |
| SCHEMBL1754974 | 0.68 | BCHE (0.54) | MEN1KMT2AGAA | |
| SCHEMBL13056575 | 0.67 | SMN1; SMN2 (0.47) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL13056572 | 0.67 | ALDH1A1 (0.37) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL23308057 | 0.66 | ALDH1A1 (0.48) | MEN1KMT2ASMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2444806-A2 | Haptens, hapten conjugates, compositions thereof and method for their preparation and use | Ventana Medical Systems, Inc. (US) | 2012-04-25 | — | — | EP | disclosed |
| EP-2444807-A2 | HAPTENS, HAPTEN CONJUGATES, COMPOSITIONS THEREOF AND METHOD FOR THEIR PREPARATION AND USE | Ventana Medical Systems, Inc. (US) | 2012-04-25 | — | — | EP | disclosed |
| EP-2442107-A2 | Haptens, hapten conjugates, compositions thereof and method for their preparation and use | Ventana Medical Systems, Inc. (US) | 2012-04-18 | — | — | EP | disclosed |