Morphine Glucuronide

SCHEMBL13268600

CN1CC[C@]23c4c5ccc(O)c4O[C@H]2[C@@H](OC2OC(C(=O)O)C(O)C(O)[C@@H]2O)C=CC3[C@H]1C5

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	OPRM1	P35372	3/20	1.00

▸	MRGPRX2	Q96LB1	2/20	1.00

▸	OPRD1	P41143	3/20	0.69

▸	OPRK1	P41145	2/20	0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Morphine Glucuronide SCHEMBL612431	1.00	OPRM1 (1.00)	OPRM1MRGPRX2OPRD1OPRK1
Morphine Glucuronide SCHEMBL6754812	1.00	OPRM1 (1.00)	OPRM1MRGPRX2OPRD1OPRK1
Morphine Glucuronide SCHEMBL17302928	1.00	OPRM1 (1.00)	OPRM1MRGPRX2OPRD1OPRK1
Morphine Glucuronide SCHEMBL152647	1.00	OPRM1 (1.00)	OPRM1MRGPRX2OPRD1OPRK1
Morphine Glucuronide SCHEMBL12082244	1.00	OPRM1 (1.00)	OPRM1MRGPRX2OPRD1OPRK1
Morphine Glucuronide SCHEMBL1743681	1.00	OPRM1 (1.00)	OPRM1MRGPRX2OPRD1OPRK1
Morphine Glucuronide SCHEMBL13267437	1.00	OPRM1 (1.00)	OPRM1MRGPRX2OPRD1OPRK1
Morphine Glucuronide SCHEMBL13245908	1.00	OPRM1 (1.00)	OPRM1MRGPRX2OPRD1OPRK1
Morphine Glucuronide SCHEMBL5674614	0.99	OPRM1 (0.98)	OPRM1MRGPRX2OPRD1OPRK1
Morphine Glucuronide SCHEMBL5674692	0.97	OPRM1 (0.94)	OPRM1MRGPRX2OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2081944-B1	NOVEL MORPHINE DERIVATIVES	NEORPHYS (FR)	2010-07-07	—	—	EP	disclosed