Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7561870 | 0.71 | MAPK1 (0.35) | MAPK1 | |
| SCHEMBL10495920 | 0.71 | — | — | |
| SCHEMBL8043484 | 0.71 | MAPK1 (0.35) | MAPK1 | |
| SCHEMBL8211972 | 0.69 | — | — | |
| SCHEMBL2023935 | 0.65 | TSHR (0.47) | MAPK1 | |
| Water SCHEMBL28814625 | 0.65 | — | — | |
| SCHEMBL30366434 | 0.63 | — | — | |
| SCHEMBL10180 | 0.61 | — | — | |
| SCHEMBL1104695 | 0.61 | — | — | |
| SCHEMBL22819 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861380-B1 | 2-(4-OXO-4H-QUINAZOLIN-3-YL)ACETAMIDES AND THEIR USE AS VASOPRESSIN V3 ANTAGONISTS | ORGANON NV (NL) | 2010-07-07 | — | — | EP | disclosed |