Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043484 | 0.79 | MAPK1 (0.35) | MAPK1ALDH1A1LMNA | |
| SCHEMBL10495920 | 0.79 | — | — | |
| SCHEMBL8211972 | 0.76 | — | — | |
| SCHEMBL28636429 | 0.73 | MAPK1 (0.32) | MAPK1 | |
| SCHEMBL2023935 | 0.71 | TSHR (0.47) | MAPK1ALDH1A1 | |
| Water SCHEMBL28814625 | 0.71 | — | — | |
| SCHEMBL13270232 | 0.71 | MAPK1 (0.31) | MAPK1 | |
| SCHEMBL263071 | 0.69 | — | — | |
| SCHEMBL10704952 | 0.69 | MAPK1 (0.35) | MAPK1 | |
| SCHEMBL30366434 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229026-A1 | ALKOXYIMINOALKANOIC ACID DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2002-08-07 | — | — | EP | disclosed |
| US-6346521-B1 | OSTEOGENESIS PROMOTERS FOR BONE DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-02-12 | — | — | US | disclosed |
| EP-0719258-B1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| EP-0719782-B1 | Optically active benzothiepin derivative, its preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-07-04 | — | — | EP | disclosed |
| US-5786367-A | OXYGEN SCAVENGERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| EP-0719782-A1 | Optically active benzothiepin derivative, its preparation and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |
| EP-0483772-B1 | Aminocoumaran derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-09-13 | — | — | EP | disclosed |
| EP-0483772-A1 | Aminocoumaran derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-05-06 | — | — | EP | disclosed |
| US-4914109-A | ANTICONVULSANTS, ANTIANXIETY AGENTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1990-04-03 | — | — | US | disclosed |
| US-4892872-A | ANTIEMETICS, ANTINAUSEA | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-01-09 | — | — | US | disclosed |
| US-4824951-A | MUSCLE RELAXANTS, ANTICONVULSANTS, ANXIOLYTIC AGENTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-04-25 | — | — | US | disclosed |
| US-4772600-A | MUSCLE RELAXANTS, ANTICONVULSANTS, ANXIOLYTIC | A. H. ROBINS COMPANY, INC. (US) | 1988-09-20 | — | — | US | disclosed |
| US-4649144-A | Antibacterial 7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid derivatives | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1987-03-10 | — | — | US | disclosed |
| US-4202895-A | 1-Polyhaloalkyl-2(1H)-quinazolinone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-05-13 | — | — | US | disclosed |
| US-4182706-A | Flame-retardant agents for phenolic resins and process for their production | CHEMISCHE FABRIK KALK GMBH (DE) | 1980-01-08 | — | — | US | disclosed |
| US-4107188-A | FOR DECREASING LIPID LEVELS | HOFFMANN-LA ROCHE INC. (US) | 1978-08-15 | — | — | US | disclosed |
| US-4105768-A | Hypotensive substituted 1,2,4-triazoles | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1978-08-08 | — | — | US | disclosed |
| US-4104285-A | OF NORCHOLANIC ACID, BISNORCHOLANIC ACID, OR ETIOCHOLANIC ACID, STEROIDS, BILE FLOW STIMULATORS, ANTILIPEMIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1978-08-01 | — | — | US | disclosed |
| US-3959476-A | Antihypertensive substituted triazoles | ASTRA LAKEMEDEL AKTIEBOLAG (SW) | 1976-05-25 | — | — | US | disclosed |