SCHEMBL8043484

SCHEMBL8043484

CC(O)C(C)(C)OOC(C)(C)C(C)O

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.35
TSHR P16473 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2023935 0.91 TSHR (0.47) MAPK1TSHRALDH1A1
SCHEMBL2027418 0.82 TSHR (0.36) MAPK1TSHRALDH1A1
SCHEMBL10495920 0.79
SCHEMBL7561870 0.79 MAPK1 (0.35) MAPK1ALDH1A1LMNA
SCHEMBL8211972 0.76
Water SCHEMBL28814625 0.71
SCHEMBL13270232 0.71 MAPK1 (0.31) MAPK1
SCHEMBL96706 0.69 TSHR (0.33) TSHR
SCHEMBL30366434 0.69
SCHEMBL9239211 0.69 TSHR (0.38) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0810212-B1 Organic peroxide stabilization with alpha-hydroxyalkyl peroxides CK WITCO CORP (US) 2000-04-05 EP claimed
EP-0810212-A2 Organic peroxide stabilization with alpha-hydroxyalkyl peroxides WITCO CORPORATION (US) 1997-12-03 EP claimed
US-5654463-A Organic peroxide stabilization with α-hydroxyalkyl peroxides WITCO CORPORATION (US) 1997-08-05 US claimed
EP-0810212-B1 Organic peroxide stabilization with alpha-hydroxyalkyl peroxides CK WITCO CORP (US) 2000-04-05 EP disclosed
EP-0810212-A2 Organic peroxide stabilization with alpha-hydroxyalkyl peroxides WITCO CORPORATION (US) 1997-12-03 EP disclosed
US-5654463-A Organic peroxide stabilization with α-hydroxyalkyl peroxides WITCO CORPORATION (US) 1997-08-05 US disclosed