Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2158554 | 0.91 | — | — | |
| SCHEMBL3814650 | 0.83 | ACLY (0.39) | LMNAACLYS1PR1HSD17B1HSD17B2 | |
| SCHEMBL2158088 | 0.75 | — | — | |
| SCHEMBL2157632 | 0.73 | MEN1 (0.40) | LMNA | |
| SCHEMBL2157474 | 0.71 | NPSR1 (0.55) | ACLYHSD17B1HSD17B2 | |
| SCHEMBL2157610 | 0.71 | NPC1 (0.33) | — | |
| SCHEMBL2157369 | 0.71 | MAPT (0.40) | LMNAMAPT | |
| SCHEMBL4764323 | 0.70 | CA12 (0.40) | LMNAHSD17B1HSD17B2 | |
| SCHEMBL2158593 | 0.70 | IKBKB (0.59) | HSD17B1HSD17B2 | |
| SCHEMBL2157626 | 0.69 | MAPT (0.56) | LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206709-A2 | Thiophene derivatives as antiviral agents for flavivirus infection | Virochem Pharma Inc. (CA) | 2010-07-14 | — | — | EP | disclosed |