Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 3/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2158554 | 0.85 | — | — | |
| SCHEMBL3814674 | 0.85 | GAA (0.40) | LMNAHSD17B1HSD17B2 | |
| SCHEMBL13270767 | 0.83 | LMNA (0.39) | ACLYS1PR1LMNAHSD17B1HSD17B2 | |
| SCHEMBL3807904 | 0.79 | HSD17B1 (0.48) | S1PR1LMNAHSD17B1HSD17B2 | |
| SCHEMBL3814771 | 0.78 | RAB9A (0.33) | S1PR1LMNA | |
| SCHEMBL3809008 | 0.74 | ALDH1A1 (0.37) | LMNA | |
| SCHEMBL3809712 | 0.72 | POLB (0.50) | ACLYHSD17B1HSD17B2 | |
| SCHEMBL3809786 | 0.72 | ACLY (0.47) | ACLYS1PR1LMNAHSD17B1HSD17B2 | |
| SCHEMBL3817235 | 0.71 | HSD17B1 (0.45) | HSD17B1HSD17B2 | |
| SCHEMBL4764323 | 0.70 | CA12 (0.40) | LMNAHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |