Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 17/20 | 0.44 |
| ▸ | MC5R | P33032 | 9/20 | 0.44 |
| ▸ | MC3R | P41968 | 3/20 | 0.42 |
| ▸ | MC1R | Q01726 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | UGCG | Q16739 | 2/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | PYGM | P11217 | 1/20 | 0.40 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13271500 | 0.87 | PYGL (0.41) | MC4RMC5RMC3RMC1RPYGL | |
| SCHEMBL13271644 | 0.84 | PYGL (0.41) | MC4RMC5RMC3RMC1RPYGL | |
| SCHEMBL14144446 | 0.84 | MC4R (0.41) | MC4RMC5RMC3RMC1R | |
| SCHEMBL13271678 | 0.80 | CYP51A1 (0.48) | MC4RMC5RMC3RMC1RPYGL | |
| SCHEMBL2608542 | 0.80 | AVPR1A (0.44) | — | |
| SCHEMBL2606824 | 0.78 | CYP51A1 (0.57) | CYP3A4UGCGPYGLPYGMCYP51A1 | |
| SCHEMBL14144445 | 0.76 | KDM4E (0.36) | MC4RMC5RMC3RPYGL | |
| SCHEMBL2608568 | 0.75 | MC4R (0.43) | MC4RMC5RMC3RMC1RPYGL | |
| SCHEMBL13271484 | 0.75 | MC4R (0.41) | MC4RCYP3A4 | |
| SCHEMBL2607048 | 0.74 | CYP51A1 (0.61) | CYP3A4UGCGPYGLPYGMCYP51A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636224-B1 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDE INHIBITORS OF GLYCOGEN PHOSHORYLASE | PROSIDION LTD (GB) | 2010-07-14 | — | — | EP | disclosed |