Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 17/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | MC5R | P33032 | 11/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MC3R | P41968 | 2/20 | 0.37 |
| ▸ | MC1R | Q01726 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13271500 | 0.85 | PYGL (0.41) | MC4RMC5RMC3RMC1R | |
| SCHEMBL13271677 | 0.84 | MC4R (0.44) | MC4RMC5RMC3RMC1R | |
| SCHEMBL13271644 | 0.79 | PYGL (0.41) | MC4RMC5RMC3RMC1R | |
| SCHEMBL2108156 | 0.79 | CYP51A1 (0.52) | KMT2AF11TP53 | |
| SCHEMBL13271678 | 0.77 | CYP51A1 (0.48) | MC4RMC5RMC3RMC1R | |
| SCHEMBL2608542 | 0.76 | AVPR1A (0.44) | MEN1KMT2A | |
| SCHEMBL14144445 | 0.74 | KDM4E (0.36) | MC4RMEN1KMT2AMC5RMC3R | |
| SCHEMBL14143435 | 0.70 | GPR132 (0.39) | MC4R | |
| SCHEMBL13271484 | 0.70 | MC4R (0.41) | MC4RMEN1KMT2A | |
| SCHEMBL2107354 | 0.69 | CYP51A1 (0.57) | MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7405210-B2 | Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phosphorylase | OSI PHARMACEUTICALS, INC. (US) | 2008-07-29 | — | — | US | disclosed |
| US-20070244090-A9 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDE INHIBITORS OF GLYCOGEN PHOSPHORYLASE | BRADLEY STUART E | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244090-A9 | PYRROLOPYRIDINE-2-CARBOXYLIC ACID AMIDE INHIBITORS OF GLYCOGEN PHOSPHORYLASE | PYGL, PYGM, PYGB | MC4R 4127/4885MEN1 4163/4885KMT2A 2476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.