Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22471423 | 0.79 | MAPT (0.59) | MAPTL3MBTL1SIRT6ALDH1A1CYP1A2 | |
| SCHEMBL29506617 | 0.74 | MAPT (0.54) | MAPTL3MBTL1SIRT6ALDH1A1CYP1A2 | |
| SCHEMBL21373389 | 0.74 | MAPT (0.54) | MAPTL3MBTL1SIRT6ALDH1A1CYP1A2 | |
| SCHEMBL21373435 | 0.73 | MAPT (0.60) | MAPTL3MBTL1SIRT6ALDH1A1CYP1A2 | |
| SCHEMBL29506628 | 0.73 | MAPT (0.60) | MAPTL3MBTL1SIRT6ALDH1A1CYP1A2 | |
| SCHEMBL21590162 | 0.71 | MAPT (0.51) | MAPTL3MBTL1SIRT6ALDH1A1CYP1A2 | |
| SCHEMBL15247376 | 0.71 | MEN1 (0.52) | ALDH1A1CYP2C19SMN1; SMN2LMNAKMT2A | |
| SCHEMBL3513303 | 0.70 | ALDH1A1 (0.50) | MAPTL3MBTL1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL11975455 | 0.69 | MAPT (0.38) | MAPTALDH1A1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL5004920 | 0.68 | KMT2A (0.40) | MAPTL3MBTL1SIRT6ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2208729-A1 | OXAZOLIDINONE DERIVATIVE HAVING 7-MEMBERED HETERO RING | Research Foundation Itsuu Laboratory (JP) | 2010-07-21 | — | — | EP | disclosed |