Mebufotenin

Mebufotenin

SCHEMBL132733

COc1ccc2[nH]cc(CCN(C)C)c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1D P28221 8/20 1.00
HTR1A P08908 6/20 1.00
HTR1B P28222 6/20 1.00
HTR6 P50406 5/20 1.00
HTR2A P28223 4/20 1.00
HTR2C P28335 3/20 1.00
HTR7 P34969 3/20 1.00
CYP1A2 P05177 2/20 1.00
CYP2D6 P10635 2/20 1.00
HTR4 Q13639 2/20 1.00
HTR1E P28566 2/20 1.00
HTR2B P41595 2/20 1.00
HTR5A P47898 2/20 1.00
HTR3E A5X5Y0 1/20 1.00
HTR3B O95264 1/20 1.00
CYP2C9 P11712 1/20 1.00
HTR1F P30939 1/20 1.00
HTR3A P46098 1/20 1.00
MTNR1A P48039 1/20 1.00
MTNR1B P49286 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mebufotenin SCHEMBL27221706 1.00 HTR1D (1.00) HTR1DHTR1AHTR1BHTR6HTR2A
Mebufotenin SCHEMBL29351950 1.00 HTR1D (1.00) HTR1DHTR1AHTR1BHTR6HTR2A
Mebufotenin SCHEMBL31098269 1.00 HTR1D (1.00) HTR1DHTR1AHTR1BHTR6HTR2A
Mebufotenin SCHEMBL26111484 0.99 HTR1D (0.97) HTR1DHTR1AHTR1BHTR6HTR2A
Mebufotenin SCHEMBL25330504 0.99 HTR1D (0.97) HTR1DHTR1AHTR1BHTR6HTR2A
Mebufotenin SCHEMBL7205139 0.92 KMT2A (1.00) HTR1DHTR1AHTR1BHTR6HTR2A
SCHEMBL8868914 0.92 HTR1D (0.85) HTR1DHTR1AHTR1BHTR6HTR2A
SCHEMBL24497000 0.92 SLC6A4 (1.00) HTR1DHTR1AHTR1BHTR6HTR2A
Mebufotenin SCHEMBL29992823 0.90 HTR1D (0.82) HTR1DHTR1AHTR1BHTR6HTR2A
Mebufotenin SCHEMBL26120710 0.90 HTR1D (0.82) HTR1DHTR1AHTR1BHTR6HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2295 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144807-A1 METHOD OF ADMINISTRATION OF A PARENTERAL FORMULATION COMPRISING A PSYCHEDELIC AGENT CYBIN UK LTD (GB) 2026-05-28 US claimed
CN-122028945-A Apparatus, systems, and methods for aerosolized drug administration GH研究爱尔兰有限公司 2026-05-12 CN claimed
US-20260124174-A1 COMPOSITIONS OF MATTER AND PHARMACEUTICAL COMPOSITIONS ATAI THERAPEUTICS INC (US) 2026-05-07 US claimed
US-20260115168-A1 COMPOSITIONS OF MATTER AND PHARMACEUTICAL COMPOSITIONS ATAI THERAPEUTICS INC (US) 2026-04-30 US claimed
US-20260114468-A1 PACKAGED FOOD MIXTURE CPRG, LLC (US) 2026-04-30 US claimed
US-20260115167-A1 NOVEL COMPOSITIONS OF MATTER AND PHARMACEUTICAL COMPOSITIONS ATAI THERAPEUTICS INC (US) 2026-04-30 US claimed
US-12612363-B2 Recrystallisation of 5-methoxy-N,N-dimethyltryptamine(5-MeO-DMT) GH Research Ireland Limited (IE) 2026-04-28 US claimed
EP-4728531-A1 BIOADAPTIVE THERAPEUTIC ENVIRONMENTS Therapod LLC (US) 2026-04-22 EP claimed
EP-4727525-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING 5-METHOXY-N,N-DIMETHYLTRYPTAMINE (5-MEO-DMT) Beckley Psytech Limited (GB) 2026-04-22 EP claimed
US-12595497-B2 Processes for the production of tryptamines COMPASS PATHFINDER LIMITED (GB) 2026-04-07 US claimed
EP-1948155-A2 PHARMACEUTICAL COMPOSITIONS COMPRISING DROXIDOPA Chelsea Therapeutics Inc. (US) 2008-07-30 EP claimed
US-20080015181-A1 Pharmaceutical Compositions Comprising Droxidopa CHELSEA THERAPEUTICS, INC. 2008-01-17 US claimed
WO-2008003028-A2 PHARMACEUTICAL COMPOSITIONS COMPRISING DROXIDOPA CHELSEA THERAPEUTICS, INC. (US) 2008-01-03 WO claimed
WO-2007110637-A1 METHOD FOR EXTRACTING TARGET ALKALOID USING AN IONIC LIQUID AS EXTRACTING SOLVENT BIONIQS LIMITED (GB) 2007-10-04 WO claimed
US-7132287-B2 Preparing culture of nervous system tissues; prepare nutrient broth containing agonist, inoculate with nervous system stem cells, propagate and recover cells PSYCHIATRIC GENOMICS, INC. (US) 2006-11-07 US claimed
US-20030082802-A1 Preparing culture of nervous system tissues; prepare nutrient broth containing agonist, inoculate with nervous system stem cells, propagate and recover cells PSYCHIATRIC GENOMICS, INC. (US) 2003-05-01 US claimed
WO-2002102988-A2 METHOD FOR NEURAL STEM CELL DIFFERENTIATION USING 5HT-1A AGONISTS PSYCHIATRIC GENOMICS, INC. (US) 2002-12-27 WO claimed
WO-2001015677-A2 USE OF 5-HT1B/1D AGONISTS TO TREAT OTIC PAIN ALCON LABORATORIES, INC. (US) 2001-03-08 WO claimed
WO-1998018458-A1 OPTHALMOLOGICAL COMPOSITIONS CONTAINING SEROTONIN 5-HT1A RECEPTOR AGONIST AND THEIR USE IN THE TREATMENT OF GLAUCOMA ALCON LABORATORIES, INC. (US) 1998-05-07 WO claimed
WO-1997044062-A1 THE USE OF 5-HT1B/1D AGONISTS TO TREAT OCULAR PAIN ALCON LABORATORIES, INC. (US) 1997-11-27 WO claimed