Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 8/20 | 1.00 |
| ▸ | HTR1A | P08908 | 6/20 | 1.00 |
| ▸ | HTR1B | P28222 | 6/20 | 1.00 |
| ▸ | HTR6 | P50406 | 5/20 | 1.00 |
| ▸ | HTR2A | P28223 | 4/20 | 1.00 |
| ▸ | HTR2C | P28335 | 3/20 | 1.00 |
| ▸ | HTR7 | P34969 | 3/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 2/20 | 1.00 |
| ▸ | HTR4 | Q13639 | 2/20 | 1.00 |
| ▸ | HTR1E | P28566 | 2/20 | 1.00 |
| ▸ | HTR2B | P41595 | 2/20 | 1.00 |
| ▸ | HTR5A | P47898 | 2/20 | 1.00 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 1.00 |
| ▸ | HTR3B | O95264 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | HTR1F | P30939 | 1/20 | 1.00 |
| ▸ | HTR3A | P46098 | 1/20 | 1.00 |
| ▸ | MTNR1A | P48039 | 1/20 | 1.00 |
| ▸ | MTNR1B | P49286 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mebufotenin SCHEMBL27221706 | 1.00 | HTR1D (1.00) | HTR1DHTR1AHTR1BHTR6HTR2A | |
| Mebufotenin SCHEMBL29351950 | 1.00 | HTR1D (1.00) | HTR1DHTR1AHTR1BHTR6HTR2A | |
| Mebufotenin SCHEMBL132733 | 1.00 | HTR1D (1.00) | HTR1DHTR1AHTR1BHTR6HTR2A | |
| Mebufotenin SCHEMBL26111484 | 0.99 | HTR1D (0.97) | HTR1DHTR1AHTR1BHTR6HTR2A | |
| Mebufotenin SCHEMBL25330504 | 0.99 | HTR1D (0.97) | HTR1DHTR1AHTR1BHTR6HTR2A | |
| Mebufotenin SCHEMBL7205139 | 0.92 | KMT2A (1.00) | HTR1DHTR1AHTR1BHTR6HTR2A | |
| SCHEMBL8868914 | 0.92 | HTR1D (0.85) | HTR1DHTR1AHTR1BHTR6HTR2A | |
| SCHEMBL24497000 | 0.92 | SLC6A4 (1.00) | HTR1DHTR1AHTR1BHTR6HTR2A | |
| Mebufotenin SCHEMBL29992823 | 0.90 | HTR1D (0.82) | HTR1DHTR1AHTR1BHTR6HTR2A | |
| Mebufotenin SCHEMBL26120710 | 0.90 | HTR1D (0.82) | HTR1DHTR1AHTR1BHTR6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240254081-A1 | CATALYTIC TRYPTAMINE PROCESSES AND PRECURSORS | KARE CHEMICAL TECHNOLOGIES INC. (CA) | 2024-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240254081-A1 | CATALYTIC TRYPTAMINE PROCESSES AND PRECURSORS | HNMT, TPSB2, TPSG1 | HTR1D 144/4885HTR1A 39/4885HTR1B 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.