Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 16/20 | 0.46 |
| ▸ | CA2 | P00918 | 16/20 | 0.46 |
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | TERT | O14746 | 3/20 | 0.45 |
| ▸ | CA4 | P22748 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14367687 | 0.94 | TERT (0.48) | CA1CA2CA12CA9TERT | |
| SCHEMBL17365333 | 0.84 | CA1 (0.52) | CA1CA2CA12CA9CA4 | |
| SCHEMBL10035654 | 0.81 | TERT (0.55) | TERTLMNA | |
| SCHEMBL10001927 | 0.81 | TERT (0.40) | CA1CA2CA12CA9TERT | |
| SCHEMBL10035653 | 0.80 | TERT (0.54) | TERTLMNA | |
| SCHEMBL23130692 | 0.80 | TERT (0.43) | CA1CA12CA9TERTLMNA | |
| SCHEMBL15161172 | 0.80 | CA1 (0.48) | CA1CA2CA12CA9TERT | |
| SCHEMBL23153405 | 0.78 | POLB (0.42) | TERTHPGD | |
| SCHEMBL10001931 | 0.76 | TERT (0.51) | TERTLMNA | |
| SCHEMBL23130696 | 0.76 | TERT (0.35) | TERTLMNACYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759459-B2 | Fluorescent assays for protein kinases | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2010-07-20 | — | — | US | disclosed |