SCHEMBL10001927

SCHEMBL10001927

Cc1cc(=O)[nH]c2cc(NC(=O)CN(CCN(CCN(CC(=O)O)CC(=O)NNC(=O)CCN3C(=O)C=CC3=O)CC(=O)O)CC(=O)O)ccc12

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 10/20 0.40
▸ CA1 P00915 9/20 0.38
▸ CA2 P00918 9/20 0.38
▸ CA4 P22748 4/20 0.38
▸ CA12 O43570 4/20 0.38
▸ CA9 Q16790 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10001934 0.89 TERT (0.49) TERT
SCHEMBL10035702 0.88 TERT (0.39) TERT
SCHEMBL14367687 0.86 TERT (0.48) TERTCA1CA2CA4CA12
SCHEMBL19274957 0.84 TERT (0.33) TERTCA1CA2CA4CA12
SCHEMBL10035607 0.82 TERT (0.50) TERT
SCHEMBL13273544 0.81 CA1 (0.46) TERTCA1CA2CA4CA12
SCHEMBL10035654 0.77 TERT (0.55) TERT
SCHEMBL10035653 0.76 TERT (0.54) TERT
SCHEMBL10001931 0.74 TERT (0.51) TERT
SCHEMBL23130692 0.74 TERT (0.43) TERTCA1CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8110404-B2 Luminescent lanthanide binding chelates BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2012-02-07 — — US disclosed
US-20080299675-A1 Luminescent Lanthanide Binding Chelates BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2008-12-04 — — US disclosed
WO-2007055700-A1 LUMINESCENT LANTHANIDE BINDING CHELATES THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2007-05-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080299675-A1 Luminescent Lanthanide Binding Chelates HLCS, LYAR, SLC6A13 TERT 2908/4885CA1 959/4885CA2 257/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback